Measuring aortic wall strength and thickness in ascending aortic aneurysms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project analyzes resected ascending aortic tissue from patients undergoing surgery for aortic root or ascending aortic aneurysms. Samples undergo standardized mechanical testing (tensile strength, stiffness) and wall-thickness measurement in the lab. Those biomechanical results will be compared with clinical and imaging data such as aortic diameter and valve morphology to look for correlations. The goal is to standardize measurements and determine whether biomechanical data add information about aortic fragility beyond diameter alone.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients undergoing cardiac surgery for either aortic root and/or ascending aortic aneurysms; • Patients that have received, understood and signed the written informed consent for this study.

Exclusion Criteria:

* Patients that have already undergone previous cardiac surgery; • Patients that present with acute aortic pathologies, such as acute aortic dissection or intramural hematoma.

Where it's running

• IRCCS Policlinico San Donato
  San Donato Milanese, Mi, Italy Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.