Clinical trial Recruiting at 1 site Observational Ages 18 and up

Evaluating cardiovascular and cerebrovascular control in healthy individuals

Official title: Cardiovascular and Cerebrovascular Control in Healthy Adult Subjects

Run by IRCCS Policlinico S. Donato · NCT05706532 · Data updated 2026-11-12

This study tests how well the heart and brain work together in healthy people by looking at their responses to changes in position.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment60 (estimated)
SponsorIRCCS Policlinico S. Donato
Academic / other
Locations1 site (San Donato Milanese, Milan)
StatusRecruiting
StartedMay 29, 2023
Main results expectedOctober 2027
Study endsOctober 2027
Registry record updatedJuly 6, 2026
Trial IDNCT05706532 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are healthy adults over the age of 18 who can provide informed consent.

Probably not a fit

Patients under 18 years old or those with autonomic nervous system diseases or dysfunctions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess autonomic function and cerebrovascular control in 60 healthy subjects through noninvasive analysis of time series variability. Participants will undergo an orthostatic challenge while their heart period, blood pressure, cerebral blood velocity, and peripheral resistances are recorded. Advanced signal processing techniques will be utilized to evaluate the interactions between autonomic cardiovascular function and cerebrovascular control. The study focuses on understanding how these systems work together in healthy individuals.

Why it matters

Potential benefit: If successful, this study could enhance our understanding of autonomic nervous system function and its impact on cardiovascular and cerebrovascular health.

How similar studies have gone: While this approach is observational and may have been explored in various forms, the specific focus on healthy subjects and advanced signal processing techniques may offer novel insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* age \>18
* sinus rhythm
* informed consent signed

Exclusion Criteria:

* age \<18
* presence of autonomic nervous system diseases or dysfunctions

Where it's running

  • IRCCS Policlinico San Donato
    San Donato Milanese, Milan, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.