Evaluating cardiovascular and cerebrovascular control in healthy individuals
Official title: Cardiovascular and Cerebrovascular Control in Healthy Adult Subjects
Run by IRCCS Policlinico S. Donato · NCT05706532 · Data updated 2026-11-12
This study tests how well the heart and brain work together in healthy people by looking at their responses to changes in position.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | IRCCS Policlinico S. Donato Academic / other |
| Locations | 1 site (San Donato Milanese, Milan) |
| Status | Recruiting |
| Started | May 29, 2023 |
| Main results expected | October 2027 |
| Study ends | October 2027 |
| Registry record updated | July 6, 2026 |
| Trial ID | NCT05706532 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy adults over the age of 18 who can provide informed consent.
✕Probably not a fit
Patients under 18 years old or those with autonomic nervous system diseases or dysfunctions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to assess autonomic function and cerebrovascular control in 60 healthy subjects through noninvasive analysis of time series variability. Participants will undergo an orthostatic challenge while their heart period, blood pressure, cerebral blood velocity, and peripheral resistances are recorded. Advanced signal processing techniques will be utilized to evaluate the interactions between autonomic cardiovascular function and cerebrovascular control. The study focuses on understanding how these systems work together in healthy individuals.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of autonomic nervous system function and its impact on cardiovascular and cerebrovascular health.
How similar studies have gone: While this approach is observational and may have been explored in various forms, the specific focus on healthy subjects and advanced signal processing techniques may offer novel insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age \>18 * sinus rhythm * informed consent signed Exclusion Criteria: * age \<18 * presence of autonomic nervous system diseases or dysfunctions
Where it's running
-
IRCCS Policlinico San Donato
San Donato Milanese, Milan, Italy Recruiting
Study contacts
- Study coordinator: Vlasta Bari, PhD
- Email: vlasta.bari@grupposandonato.it
- Phone: +390252774381
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.