Evaluating cardiovascular and cerebrovascular control in healthy individuals
Cardiovascular and Cerebrovascular Control in Healthy Adult Subjects
IRCCS Policlinico S. Donato · NCT05706532
This study tests how well the heart and brain work together in healthy people by looking at their responses to changes in position.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | IRCCS Policlinico S. Donato (other) |
| Locations | 1 site (San Donato Milanese, Milan) |
| Trial ID | NCT05706532 on ClinicalTrials.gov |
What this trial studies
This study aims to assess autonomic function and cerebrovascular control in 60 healthy subjects through noninvasive analysis of time series variability. Participants will undergo an orthostatic challenge while their heart period, blood pressure, cerebral blood velocity, and peripheral resistances are recorded. Advanced signal processing techniques will be utilized to evaluate the interactions between autonomic cardiovascular function and cerebrovascular control. The study focuses on understanding how these systems work together in healthy individuals.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults over the age of 18 who can provide informed consent.
Not a fit: Patients under 18 years old or those with autonomic nervous system diseases or dysfunctions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of autonomic nervous system function and its impact on cardiovascular and cerebrovascular health.
How similar studies have performed: While this approach is observational and may have been explored in various forms, the specific focus on healthy subjects and advanced signal processing techniques may offer novel insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age \>18 * sinus rhythm * informed consent signed Exclusion Criteria: * age \<18 * presence of autonomic nervous system diseases or dysfunctions
Where this trial is running
San Donato Milanese, Milan
- IRCCS Policlinico San Donato — San Donato Milanese, Milan, Italy (RECRUITING)
Study contacts
- Study coordinator: Vlasta Bari, PhD
- Email: vlasta.bari@grupposandonato.it
- Phone: +390252774381
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Healthy, Autonomic Nervous System, Cerebral Autoregulation, autonomic nervous system, heart rate variability, cerebral autoregulation, peripheral resistances