Monitoring system to predict kidney injury after heart surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to validate a predictive algorithm called the Multifactorial Dynamic Perfusion Index (MDPI) that assesses the risk of postoperative acute kidney injury in patients undergoing cardiac surgery with cardiopulmonary bypass. The study will involve 800 adult patients and 200 infants, collecting dynamic hemodynamic and clinical parameters during surgery to enhance the predictive accuracy of the MDPI. The goal is to develop a monitoring tool that allows for real-time adjustments during surgery to potentially prevent kidney injury. The study is structured into three work packages focusing on validation, development for infants, and exploration of additional outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* patients undergoing cardiac surgery with cardiopulmonary bypass
* patients \>18 years for WP1 and WP3; patients \<6 years and weight \<20 kg for WP2
* willingness to participate and sign the informed consent

Exclusion Criteria:

* chronic renal failure on dyalisis for WP1 and WP3
* emergency surgery for all WP
* refusal to partecipate

Where it's running

• IRCCS Policlinico San Donato
  San Donato Milanese, Milano, Italy Recruiting

Study contacts

• Study coordinator: Marco Ranucci, Medicine and Surgery
• Email: marco.ranucci@grupposandonato.it
• Phone: 0252774754

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.