Psychological support for adults with Marfan syndrome

Psychological Help in Patients With Marfan Syndrome: the Role of Quality of Life, Coping Mechanisms, Psychosocial Aspects and Self-esteem Levels

Observational IRCCS Policlinico S. Donato · NCT05712577

This study looks at why adults with Marfan syndrome seek psychological support and how their condition affects their mental health and coping skills.

Quick facts

Study typeObservational
Enrollment125 (estimated)
Ages18 Years and up
SexAll
SponsorIRCCS Policlinico S. Donato Academic / other
Locations1 site (San Donato Milanese, Lombardia)
Trial IDNCT05712577 on ClinicalTrials.gov

What this trial studies

This observational study aims to identify the factors that lead adult patients with Marfan syndrome to seek psychological support. It will explore how the clinical manifestations of Marfan syndrome affect psychosocial aspects, self-esteem, and coping mechanisms. Participants will undergo psychological interviews and complete various self-report questionnaires to assess their mental health and quality of life. The study focuses on understanding the internal variables that drive the need for psychological support among these patients.

Who should consider this trial

Good fit: Ideal candidates for this study are adults diagnosed with Marfan syndrome who are currently receiving follow-up care at the Cardiovascular Genetic Centre.

Not a fit: Patients with cognitive deficits may not benefit from this study due to the nature of the assessments involved.

Why it matters

Potential benefit: If successful, this study could enhance the psychological well-being and quality of life for patients with Marfan syndrome.

How similar studies have performed: While there may be limited studies specifically targeting psychological support in Marfan syndrome, similar approaches in other rare diseases have shown promise in improving patient outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subjects affected by Marfan syndrome;
* Subjects currently in follow-up at Cardiovascular Genetic Centre, IRCCS Policlinico San Donato;
* Signed informed consent.

Exclusion Criteria:

* Subjects with cognitive deficits

Where this trial is running

San Donato Milanese, Lombardia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Rare DiseasesMarfan SyndromePsychology, SocialMarfan syndromePsychological supportSelf-report
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.