Clinical trial Recruiting at 1 site Observational

Examining the TMEM230 gene's role in atherosclerosis

Official title: Role of T-Mem GEne in the Molecular Pathogenesis of Atherosclerosis

Run by IRCCS Policlinico S. Donato · NCT06230406 · Data updated 2026-11-12

This study is trying to see how the TMEM230 gene affects atherosclerosis in patients by looking at tissue and blood samples to better understand the condition.

More Atherosclerosis trials

Quick facts

Study typeObservational
SexAll
Enrollment12 (estimated)
SponsorIRCCS Policlinico S. Donato
Academic / other
Locations1 site (San Donato Milanese, Milan)
StatusRecruiting
StartedSeptember 28, 2023
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedApril 7, 2026
Trial IDNCT06230406 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adult patients over 18 years old who are undergoing surgical treatment for arterial or venous vascular pathologies.

Probably not a fit

Patients with vascular pathologies that are not suitable for surgical intervention will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on understanding the modulation of the TMEM230 gene in patients with vascular pathologies, particularly atherosclerosis. It involves collecting and analyzing approximately 12 samples of vascular tissue from surgical procedures, alongside venous blood samples. The study aims to uncover the molecular mechanisms of atherosclerosis by examining genetic factors and their interactions with various risk factors. The findings could provide insights into the underlying causes of atherosclerosis and potential therapeutic targets.

Why it matters

Potential benefit: If successful, this study could lead to a better understanding of atherosclerosis and inform new treatment strategies for patients.

How similar studies have gone: While the specific approach of analyzing the TMEM230 gene in this context may be novel, previous studies have explored genetic factors in atherosclerosis with varying degrees of success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* adult patients (age \> 18 years)
* consent to participate in the study,
* patients coming to the Vascular Surgery Unit I of the IRCCS Policlinico San Donato for a vascular pathology of the arterial or venous district worthy of surgical treatment.

Exclusion Criteria:

* minor patients,
* patients who have not given their consent to participate in the study,
* patients who have vascular pathologies of the arterial or venous district not susceptible to surgical intervention.

Where it's running

  • I.R.C.C.S. Policlinico San Donato
    San Donato Milanese, Milan, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.