Evaluating Clopidogrel Resistance in Patients Undergoing Carotid Stenting

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational multicentric study aims to assess the differences in outcomes between patients who respond to Clopidogrel and those who do not, specifically focusing on the use of Ticagrelor in non-responders undergoing carotid stenting. The study will collect clinical data, including patient demographics, cardiovascular risk factors, and laboratory results, to identify factors associated with Clopidogrel resistance. Patients will be followed up at multiple intervals post-procedure to monitor for major adverse cardiovascular events and bleeding complications. The goal is to improve understanding of antiplatelet therapy effectiveness in this patient population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* adult patients (age\> 18 years)
* patients who have given their consent to participate in the study, belonging to the U.O. of Vascular Surgery of the IRCCS Policlinico San Donato and the U.O. of Vascular Surgery of the participating centers and subjected to the treatment of carotid stenosis by stenting technique.

Exclusion Criteria:

* underage patients
* patients who have not given their consent to participate in the study,
* patients who have carotid stenosis not susceptible to intervention by stenting
* pregnant or lactating women (such as situations in which carotid stenting is contraindicated regardless of the execution of the study).

Where it's running

• IRCCS Policlinico San Donato
  San Donato Milanese, Milan, Italy Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.