Finding ways to prevent lung injury caused by ventilators in patients with severe respiratory issues.
Predicting and Preventing Ventilator-Induced Lung Injury
This study is looking at ways to make breathing machines safer for people with acute respiratory distress syndrome (ARDS) by creating a system that helps doctors adjust the machines to better fit each patient's needs, which could lead to better recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11003305 on NIH RePORTER |
What this research studies
This research focuses on acute respiratory distress syndrome (ARDS), a serious condition that leads to rapid respiratory failure. It aims to improve mechanical ventilation strategies to prevent additional lung injury caused by the ventilators themselves. By developing a real-time feedback system that assesses the risk of ventilator-induced lung injury (VILI), the study seeks to tailor ventilation protocols to individual patient needs, potentially improving outcomes for those affected by ARDS. The research involves both computational modeling and clinical evaluations to refine these ventilation strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with acute respiratory distress syndrome requiring mechanical ventilation.
Not a fit: Patients with chronic respiratory conditions or those not requiring mechanical ventilation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of lung injury in ARDS patients, improving survival rates and recovery outcomes.
How similar studies have performed: Previous research has shown promise in improving ventilation strategies for ARDS, indicating that this approach could lead to meaningful advancements in patient care.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Smith, Bradford J — University of Colorado Denver
- Study coordinator: Smith, Bradford J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.