Understanding how to protect lung tissue during mechanical ventilation in patients with severe respiratory distress

Who could benefit from this research

What this research studies

This research investigates the mechanisms behind ventilator-induced lung injury (VILI) in patients suffering from acute respiratory distress syndrome (ARDS). It aims to identify optimal ventilation strategies that balance lung injury and repair, as current treatments are limited. By studying the timing of ventilatory cycles and their effects on lung tissue integrity, the research seeks to develop better management approaches for ARDS patients. The methodology includes both in vivo and in vitro experiments to understand the dynamics of lung repair and injury.

Why it matters

Where this research is happening

• University of Vermont & St Agric College
  Burlington, United States Active

Researchers

• Principal investigator: Bates, Jason Ht — University of Vermont & St Agric College
• Study coordinator: Bates, Jason Ht

Related research

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.