Condition

Ventilator Associated Pneumonia clinical trials and research

• 14Clinical trials
• 4NIH research projects
• 24Countries

Newest Ventilator Associated Pneumonia clinical trials

All recruiting trials (14)

• Probiotics to Prevent Pneumonia in Critically Ill Kids in the PICU

  We’re testing whether giving probiotics to critically ill children on a ventilator helps prevent ventilator-associated pneumonia.

  Recruiting Tanta University · Tanta, Al Gharbia · NCT07848165

• B Lymphocyte Populations in the Lungs of ICU Patients on Ventilation

  This study tests the presence and roles of B lymphocytes in the lungs of adults on invasive ventilation, to see how humoral immunity relates to ventilator-associated pneumonia.

  Recruiting University Hospital, Limoges · Limoges · NCT07436780

• Lactoferrin to help prevent infections in ventilated newborns

  This study tests whether giving lactoferrin to ventilated neonates can help prevent ventilator-associated pneumonia and related complications.

  Recruiting Tanta University · Tanta · NCT07255742

• Measuring breathing effort before and after removing the breathing tube

  This will test a new electrical impedance method to measure breathing effort in adults on ventilators as they try breathing on their own and after the breathing tube is removed.

  Recruiting University Health Network, Toronto · Toronto, Ontario · NCT07017608

• Rapid multiplex PCR on bronchoalveolar lavage to guide antibiotics for ventilator-associated pneumonia

  This trial tests whether using a fast multiplex PCR on bronchoalveolar lavage samples helps doctors choose the right antibiotics sooner for adults on mechanical ventilation suspected of ventilator-associated pneumonia.

  Recruiting CHU de Reims · Reims · NCT06554327

• Using acyclovir to treat pneumonia in ventilated patients with herpes simplex virus

  This study is testing if giving acyclovir to ICU patients on ventilators who have pneumonia and herpes simplex virus can help them survive better than those who don't receive the medication.

  Recruiting at 28 sites Phase 3 Jena University Hospital · Freiburg im Breisgau, Baden-Wurttemberg and 27 other locations · NCT06134492

• Standardized oral care using human milk for premature infants in the NICU

  This study is trying to see if giving regular oral care using human milk can help very low birth weight babies in the NICU stay healthier and avoid complications.

  Recruiting University of Florida · Gainesville, Florida · NCT06000761

• Early treatment with targeted antibiotics for severe infections using rapid diagnostics

  This study is testing if giving targeted antibiotics right away, based on quick test results, can help hospitalized patients with severe infections caused by tough-to-treat bacteria feel better faster than standard care.

  Recruiting at 21 sites Phase 4 National University of Singapore · Vellore and 20 other locations · NCT05979545

• Understanding how white blood cells affect lung inflammation in patients on ventilators

  This study is trying to see how a type of white blood cell affects lung inflammation in adults on ventilators, especially those with Acute Respiratory Distress Syndrome, to help improve treatments for lung injuries.

  Recruiting National Jewish Health · Denver, Colorado · NCT05767671

• Observational study on Ventilator Associated Pneumonia in ICUs

  This study is trying to set up a network of ICUs to help find better ways to prevent and treat Ventilator Associated Pneumonia in patients on mechanical ventilation.

  Recruiting at 22 sites European Clinical Research Alliance for Infectious Diseases (ECRAID) · Tirana and 34 other locations · NCT05719259

• Using cotrimoxazole to treat pneumonia in ICU patients

  This study is testing if cotrimoxazole can effectively treat pneumonia in ICU patients on ventilators, compared to standard antibiotics, to see if it helps them recover better.

  Recruiting at 2 sites Phase 3 Assistance Publique - Hôpitaux de Paris · Amiens and 29 other locations · NCT05696093

• Finding early biological signs of severe illness in ICU patients

  The study will collect blood, lung, and rectal samples from adults newly admitted to the ICU to see if early biological signs can help diagnose and personalize care for sepsis, ARDS, or other critical illnesses.

  Recruiting London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario · NCT05591924

• Reducing antibiotic use for pneumonia in ICU patients on ventilators

  This study tests if shorter courses of antibiotics can effectively treat pneumonia in ICU patients on ventilators while helping to prevent antibiotic resistance.

  Recruiting Assistance Publique - Hôpitaux de Paris · Clichy-sous-Bois · NCT05124977

• Measuring lung mechanics in patients on mechanical ventilation

  This study is testing how mechanical ventilation affects lung function in patients with breathing problems to help improve their care and reduce lung injury.

  Recruiting Göteborg University · Gothenburg, Västra Götaland County · NCT04484727

NIH-funded research (4)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Machine learning to map microbiome changes in ventilator-associated pneumonia

  A machine-learning guided study will analyze 16S microbiome data from mechanically ventilated patients to help identify and diagnose ventillator-associated pneumonia earlier.

  NIH research University of New Haven · West Haven, United States · NIH-11424131

• Personalizing antibiotic treatment for pneumonia in patients on ventilators

  This study is looking to make the treatment of ventilator-associated pneumonia better by finding ways to personalize how long patients need antibiotics, so they get the right care without extra side effects.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11118911

• Detecting pneumonia in patients on ventilators

  This study is working on a new, gentle way to help doctors find out if patients on ventilators have pneumonia by collecting tiny particles from their breath, which could lead to quicker and more accurate treatment for those at risk.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10820510

• Using modified endotracheal tubes to reduce pneumonia in critically ill patients

  This study is looking at a new kind of breathing tube that might help prevent pneumonia in seriously ill patients on ventilators, and it will compare this new tube to a regular one to see if it makes a difference in keeping patients healthier.

  NIH research Duke University · Durham, United States · NIH-10657255

Related topics

Quick answers

How many Ventilator Associated Pneumonia clinical trials are recruiting right now?

14, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 24 countries. The most sites are in France (5 trials), Germany (2 trials), Canada (2 trials), Egypt (2 trials), United States (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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