Condition
Psoriatic Arthritis clinical trials and research
As of November 12, 2026, Find a Trial lists 36 Psoriatic Arthritis clinical trials that are recruiting, at sites in 37 countries (most in United States (13), France (8), Canada (6)). By phase: Phase 2 (3), Phase 1 (3), Phase 3 (2), Phase 4 (1). The most active sponsors are AbbVie (2), University of California, San Diego (2), South Valley University (2). There are also 8 NIH-funded research projects on Psoriatic Arthritis, with $2.4 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 36Clinical trials
- 8NIH research projects
- 37Countries
Newest Psoriatic Arthritis clinical trials
All recruiting trials (36)
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HLA B Leader in Psoriatic Arthritis
This study tests whether the HLA B leader gene is more common in people with psoriatic arthritis than in healthy individuals.
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TaVNS for Psoriatic Arthritis in Adults
This study tests whether non-invasive taVNS can help reduce disease activity and improve pain and quality of life in adults with psoriatic arthritis.
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TQH3906 capsules for active psoriatic arthritis in adults
This trial tests whether TQH3906 capsules help people with active psoriatic arthritis more than a placebo over 12 weeks.
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Picankibart for people with active psoriatic arthritis
This trial tests whether subcutaneous picankibart can improve joint and skin symptoms in adults with active psoriatic arthritis who have not had enough benefit from NSAIDs or non-biologic DMARDs.
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Bimekizumab by IV infusion versus subcutaneous injection for adults with psoriatic arthritis or axial spondyloarthritis
This trial tests whether bimekizumab given by intravenous (IV) infusion behaves the same in the body as the usual subcutaneous injection in adults with psoriatic arthritis or axial spondyloarthritis.
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Continued daily zasocitinib treatment for adults with psoriatic arthritis
This extension will try daily zasocitinib in adults with psoriatic arthritis who completed a year of earlier treatment to see how well it works and how safe it is over about two years.
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Creating Health online course for people with rheumatological conditions
This project will test whether an online course about diet and self-care helps adults with rheumatoid arthritis, Sjogren's syndrome, lupus, mixed connective tissue disease, or psoriatic arthritis reduce fatigue and improve quality of life.
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TRAF3IP2 gene variation (rs13190932) in people with psoriasis and psoriatic arthritis
This trial will test whether the TRAF3IP2 (rs13190932) gene variant changes how adults with psoriasis or psoriatic arthritis respond to methotrexate treatment.
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Follow-up care for new cases of polyarthritis in children and young adults
This program will try standardized medical follow-up for children and young adults (≤50) with new-onset JIA, RA, psoriatic/seronegative/undifferentiated arthritis, SLE, or diffuse systemic sclerosis who are treatment-naïve or treated ≤3 months to see if more patients reach disease control or remission.
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Assessing Bimekizumab Levels in Breast Milk of Nursing Mothers
This study tests how much of the medication bimekizumab is found in the breast milk of mothers who have been using it for at least 12 weeks after giving birth to see if it's safe for their babies.
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Investigating a genetic polymorphism in Egyptian patients with psoriatic arthritis
This study is testing if a specific gene variation affects how Egyptian patients with psoriatic arthritis respond to treatment with methotrexate compared to a placebo.
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Targeted therapies for treating active psoriatic arthritis in adults
This study is testing if two different treatments for active psoriatic arthritis can help adults feel better and improve their symptoms.
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IL-17 and brain changes that link psoriatic disease to depressive symptoms
We will test whether blocking the immune protein IL-17 in adults with psoriatic disease reduces brain inflammation and improves depressive symptoms.
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Assessing long-term use of Risankizumab for Psoriatic Arthritis
This study is testing how well Risankizumab works over a long time for adults with psoriatic arthritis who haven't had enough relief from other treatments.
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Assessing Psoriatic Arthritis Activity with Ultrasound
This study is testing how well ultrasound can help track disease activity and treatment response in people with psoriatic arthritis.
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Testing Zasocitinib for Psoriatic Arthritis in Adults
This study is testing a new medication called zasocitinib to see if it can help adults with active psoriatic arthritis who haven't tried biologic treatments before.
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Exploring how Guselkumab therapy affects liver and joint health in Psoriatic Arthritis patients with NAFLD
This study is testing how a treatment called Guselkumab can help people with Psoriatic Arthritis who also have liver problems, to see if it improves their joint and liver health.
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Evaluating Upadacitinib for Psoriatic Arthritis and Spondyloarthritis
This study is testing if Upadacitinib can help people with active Psoriatic Arthritis and Spondyloarthritis feel better compared to a placebo.
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Improving Psoriatic Arthritis Screening for Patients with Plaque Psoriasis
This study is testing a new way to help doctors spot psoriatic arthritis earlier in patients with plaque psoriasis by adding extra questions and images to a screening tool.
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Study on how diet affects autoimmune diseases in rheumatology patients
This study looks at how changing to a healthier diet, like the Mediterranean diet, might help people with autoimmune diseases feel better and manage their symptoms.
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Analyzing how sex and gender affect treatment responses in psoriatic arthritis
This study looks at how being male or female affects how well new treatments work for people with psoriatic arthritis.
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Observational study on psoriasis and its risk for arthritis
This study is trying to find out which adults with psoriasis are more likely to develop psoriatic arthritis so that steps can be taken to prevent it.
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Examining cytokine levels in psoriasis and psoriatic arthritis patients
This study is trying to see how certain proteins in the blood and skin of people with psoriasis and psoriatic arthritis can help us understand these conditions better.
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Comparing imaging-based treatment strategies for psoriatic arthritis
This study is testing if using imaging scans along with regular check-ups can help people with psoriatic arthritis achieve better long-term health results than just regular check-ups alone.
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Biobank for patients with inflammatory chronic diseases and osteoporosis
This study is creating a biobank to collect samples from patients with chronic inflammatory diseases and osteoporosis to see if they can find markers that help doctors choose better treatments.
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Using capsule fecal microbiota transplantation to treat newly diagnosed chronic inflammatory diseases
This study is testing if taking capsules containing healthy gut bacteria can help people recently diagnosed with chronic inflammatory diseases feel better.
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Evaluating patient satisfaction in joint rheumatologist and dermatologist consultations for psoriatic arthritis
This study is trying to see if having both a rheumatologist and a dermatologist work together in appointments makes people with psoriatic arthritis feel more satisfied and helps them manage their condition better.
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Educational tool for melanoma patients with autoimmune diseases
This study is testing a new educational tool to help melanoma patients with autoimmune diseases understand their treatment options better and see how easy it is for them to use.
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Registry and biorepository for rheumatic diseases
This study is collecting samples and health information from adults with rheumatic diseases at Yale clinics to help researchers learn more about these conditions and improve future treatments.
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Creating a database for patients with immune-mediated inflammatory diseases
This study is creating a database and biobank for patients with immune-related diseases to see if new information can help improve treatments and understand their conditions better.
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Understanding chronic inflammatory systemic diseases and their treatments
This study looks at patients with chronic inflammatory diseases to see how these conditions are related and how they can be treated better.
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Using nivolumab to treat patients with autoimmune disorders and advanced cancer
This study is testing if nivolumab can safely help people with autoimmune disorders who also have advanced cancer by looking at how well it works and what side effects it might cause.
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Immune cells and inflammation in Achilles tendon enthesitis of psoriatic arthritis
This research will look at immune cells and inflammatory markers in Achilles tendon tissue from people with psoriatic arthritis and enthesitis to see if specific cell types relate to pain, imaging, or short-term remission.
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Monitoring pregnancy outcomes for women exposed to Stelara and Tremfya
This study is tracking pregnancies in women who have used Stelara or Tremfya to see how these medications might affect the health and development of their babies.
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Registry for patients with rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis receiving biologics
This study is collecting information from patients with rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis who are using biologic treatments to see how these medications work in real life.
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Registry for long-term treatment outcomes of psoriasis and psoriatic arthritis in Germany
This study is tracking the long-term results of different treatments for people with moderate to severe psoriasis and psoriatic arthritis in Germany to see how well they work and what side effects they may have.
NIH-funded research (8)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Precision monitoring of Psoriatic Arthritis treatment using at-home RNA sampling and smartphone data
A new study will track how Psoriatic Arthritis patients respond to TNF-inhibitor therapy using at-home RNA sampling and a remote smartphone app to collect data.
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Spine inflammation in psoriatic arthritis
We will use a new total-body PET/CT scan with an FDG tracer to find and measure spinal inflammation in people with psoriatic arthritis that affects the spine.
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Investigating how IL-17A contributes to psoriatic arthritis
This study is looking at how a protein called IL-17A contributes to psoriatic arthritis, which causes joint pain and inflammation, using a special animal model to find new ways to help people with this condition feel better.
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Improving Treatment Monitoring for Early Psoriatic Arthritis
This project aims to find better ways to track how well treatments work for people with early psoriatic arthritis by using at-home RNA samples and smartphone data.
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Understanding the causes of ongoing joint pain in people with psoriatic arthritis
This study is looking at what causes ongoing joint pain in people with psoriatic arthritis, using special imaging techniques to better understand both the physical and emotional aspects of pain, with the goal of finding better ways to help manage it.
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Understanding spinal inflammation in axial psoriatic arthritis
This study is looking at how inflammation affects the spine in people with axial psoriatic arthritis, using special imaging techniques to get a clearer picture of what's happening, which could help doctors diagnose and treat this condition better.
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Understanding how different traits and genes affect treatment responses in psoriatic arthritis
This study is looking at how different traits and genes in people with psoriatic arthritis can affect how well treatments work for them, so we can find better, personalized options for managing their condition.
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Investigating how sleep quality affects inflammation and disease activity in psoriatic arthritis.
This study is looking at how sleep quality affects people with psoriatic arthritis and how their condition might also impact their sleep, so if you have psoriatic arthritis, your experiences could help us understand this connection better over the next year!
Related topics
Quick answers
How many Psoriatic Arthritis clinical trials are recruiting right now?
36, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 37 countries. The most sites are in United States (13 trials), France (8 trials), Canada (6 trials), Germany (6 trials), Czechia (5 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 3, Phase 1: 3, Phase 3: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.