Condition

Ankylosing Spondylitis clinical trials and research

• 21Clinical trials
• 4NIH research projects
• 1New in 30 days
• 13Countries

Newest Ankylosing Spondylitis clinical trials

All recruiting trials (21)

• HB0017 Injection safety and PK in low-weight adults at different injection sites

  This early-phase study tests a single subcutaneous HB0017 injection in healthy, low-weight adults and compares how the body processes the drug when injected at different sites.

  Recruiting Phase 1 Huabo Biopharm Co., Ltd. · Hangzhou, Zhejiang · NCT07920861

• Surface topography and spine damage in radiographic axial spondyloarthritis

  This study tests whether a radiation-free 3D surface topography method can reflect spine damage and sagittal balance in adults with radiographic axial spondyloarthritis.

  Recruiting Ankara Etlik City Hospital · Ankara, Yenimahalle · NCT07855393

• New modified acupotomy method for ankylosing spondylitis

  This study tests whether a modified ultrasound-guided acupotomy can reduce disease activity and symptoms in adults (18–75) with active ankylosing spondylitis (BASDAI ≥4) compared with a sham procedure.

  Recruiting China-Japan Friendship Hospital · Henan, Zhengzhou · NCT07578220

• How different types of low back pain affect function and quality of life in people with ankylosing spondylitis.

  This single-visit project will see if different types of low back pain in adults with ankylosing spondylitis relate to pain severity, daily function, and quality of life.

  Recruiting Konya Beyhekim Training and Research Hospital · Konya, Selçuklu · NCT07510789

• Testing 608 in adults with active ankylosing spondylitis

  This trial tests whether the medicine 608 helps adults with active ankylosing spondylitis and is safe to use.

  Recruiting Phase 3 Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. · Beijing, Beijing Municipality · NCT07261644

• LNK01001 for adults with ankylosing spondylitis

  This trial will test whether taking LNK01001 twice daily helps adults with active ankylosing spondylitis reduce pain and inflammation compared with placebo.

  Recruiting Phase 3 Lynk Pharmaceuticals Co., Ltd · Beijing · NCT07237568

• Gluten-free diet effects in people with ankylosing spondylitis

  This will try an 8-week gluten-free diet to see if it reduces gut leakiness and improves symptoms and function in adults with ankylosing spondylitis.

  Recruiting Saglik Bilimleri Universitesi · Istanbul and 3 other locations · NCT07166874

• Evaluating neck muscles and balance in men with ankylosing spondylitis

  This study is testing how the strength of neck muscles affects balance in men with ankylosing spondylitis compared to healthy men.

  Recruiting Istanbul Physical Medicine Rehabilitation Training and Research Hospital · Istanbul, Bahcelievler · NCT06967883

• Evaluating secukinumab effectiveness in Korean patients with ankylosing spondylitis

  This study is testing how well secukinumab works for Korean patients with ankylosing spondylitis who haven't tried other treatments before.

  Recruiting at 3 sites Novartis · Jinju, Gyeongsangnam-do and 2 other locations · NCT06905288

• Identifying biomarkers for early diagnosis of inflammatory rheumatic diseases

  This study is trying to find specific markers in the body that can help doctors diagnose inflammatory rheumatic diseases like Ankylosing Spondylitis, Rheumatoid Arthritis, and Systemic Lupus Erythematosus earlier and more accurately.

  Recruiting Universidade Nova de Lisboa · Lisbon · NCT06778343

• Fecal microbiota transplantation for treating axial spondyloarthritis

  This study is testing if a treatment using gut bacteria from healthy donors can help people with axial spondyloarthritis who aren't feeling better with their current medications.

  Recruiting Phase 2 University Hospital of North Norway · Tromsø · NCT06451588

• Study on how diet affects autoimmune diseases in rheumatology patients

  This study looks at how changing to a healthier diet, like the Mediterranean diet, might help people with autoimmune diseases feel better and manage their symptoms.

  Recruiting University of Central Florida · Orlando, Florida · NCT06339957

• Analyzing the microbiome in Korean patients with ankylosing spondylitis

  This study is trying to see how the gut bacteria of Korean patients with ankylosing spondylitis might be connected to their condition by collecting and analyzing samples from them and their families.

  Recruiting at 2 sites Hanyang University Seoul Hospital · Seoul, Kyungheedae-ro 23 and 1 other locations · NCT06076083

• Comparing Jitongning tablets to placebo for treating spondyloarthritis

  This study is testing if Jitongning tablets can help people with active ankylosing spondylitis feel better compared to a placebo.

  Recruiting at 10 sites Phase 3 Tasly Pharmaceutical Group Co., Ltd · Beijing, Beijing Municipality and 9 other locations · NCT06000956

• Registry for evaluating a comprehensive approach to autoimmune disorders

  This study is testing a personalized treatment program for people with autoimmune disorders to see if combining different therapies helps them feel better over time.

  Recruiting AndHealth · Columbus, Ohio · NCT05883371

• Long-term follow-up on shoulder arthroplasty outcomes

  This study is looking at how well shoulder replacement surgery works over time by following patients for at least 10 years to see how they feel and how their shoulders are doing.

  Recruiting at 40 sites Exactech · Laguna Woods, California and 39 other locations · NCT05603728

• Using capsule fecal microbiota transplantation to treat newly diagnosed chronic inflammatory diseases

  This study is testing if taking capsules containing healthy gut bacteria can help people recently diagnosed with chronic inflammatory diseases feel better.

  Recruiting Phase 2 Odense University Hospital · Odense · NCT04924270

• Educational tool for melanoma patients with autoimmune diseases

  This study is testing a new educational tool to help melanoma patients with autoimmune diseases understand their treatment options better and see how easy it is for them to use.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT04751396

• Registry and biorepository for rheumatic diseases

  This study is collecting samples and health information from adults with rheumatic diseases at Yale clinics to help researchers learn more about these conditions and improve future treatments.

  Recruiting Yale University · New Haven, Connecticut · NCT04402086

• Analyzing gut bacteria in patients with spondyloarthritis receiving treatment

  This study is trying to see how gut bacteria might affect how well people with spondyloarthritis respond to a specific treatment.

  Recruiting Region Skane · Lund · NCT03839862

• Registry for patients with rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis receiving biologics

  This study is collecting information from patients with rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis who are using biologic treatments to see how these medications work in real life.

  Recruiting Seoul National University Hospital · Seoul · NCT01965132

NIH-funded research (4)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• CARD9 and Ankylosing Spondylitis: understanding immune signals in veterans

  A study with veterans who have ankylosing spondylitis will explore how immune signals linked to CARD9 may influence disease and treatment responses.

  NIH research VA Eastern Colorado Health Care System · Aurora, UNITED STATES · NIH-11400852

• How the gene CARD9 may affect ankylosing spondylitis

  Researchers are looking at whether differences in a gene called CARD9 help explain inflammation and treatment response in people with ankylosing spondylitis.

  NIH research Portland VA Medical Center · Portland, United States · NIH-11116936

• Understanding how spinal disease progresses in ankylosing spondylitis

  This study is looking at how ankylosing spondylitis affects the spine over time, and it aims to find specific markers in your blood that can help predict how severe the damage might get, so we can catch problems early and take better care of you.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11039825

• Investigating the role of CARD9 in Ankylosing Spondylitis

  This study is looking at how genes and immune cells affect Ankylosing Spondylitis in veterans, with the goal of finding better ways to predict and personalize treatments for this painful condition.

  NIH research Portland VA Medical Center · Portland, United States · NIH-10807453

Related topics

Quick answers

How many Ankylosing Spondylitis clinical trials are recruiting right now?

21, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in China (5 trials), United States (5 trials), Turkey (Türkiye) (4 trials), South Korea (3 trials), Sweden (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 3, Phase 2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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