Improving Treatment Monitoring for Early Psoriatic Arthritis
Precision Monitoring of Treatment Response in Early Psoriatic Arthritis: Integrating at-Home RNA Microsampling into Ongoing, Remote, Smart Phone-Based, Digital Data Capturing
This project aims to find better ways to track how well treatments work for people with early psoriatic arthritis by using at-home RNA samples and smartphone data.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11113855 on NIH RePORTER |
What this research studies
Many people with psoriatic arthritis don't respond well to common treatments like TNF inhibitors, and doctors don't always know why. This project wants to change that by using a new approach that combines small RNA samples collected at home with digital information gathered through smartphones. Researchers will use advanced computer methods to look for patterns in this data, hoping to understand why some treatments work for certain individuals and others don't. The goal is to develop a more personalized way to monitor treatment effectiveness, right from your own home.
Who could benefit from this research
Good fit: Ideal candidates for this type of research would be adults aged 21 and older who have been diagnosed with early psoriatic arthritis.
Not a fit: Patients without psoriatic arthritis or those not receiving treatments for the condition would not directly benefit from this specific monitoring approach.
Why it matters
Potential benefit: If successful, this work could lead to more precise and personalized treatment plans for psoriatic arthritis, helping patients find the right therapy faster and avoid ineffective medications.
How similar studies have performed: While current treatments have improved outcomes for many, this approach uses novel at-home monitoring and machine learning to address the significant challenge of treatment non-response, building on existing knowledge of disease pathogenesis.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Scher, Jose U. — New York University School of Medicine
- Study coordinator: Scher, Jose U.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.