Assessing Psoriatic Arthritis Activity with Ultrasound
A Single Centre Prospective Cohort Study of Classification and Activity Assessment of Psoriatic Arthritis Based on Power Doppler (PD) Ultrasonography (PDUS)
This study is testing how well ultrasound can help track disease activity and treatment response in people with psoriatic arthritis.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Nanjing Medical University Academic / other |
| Locations | 2 sites (Nanjing, Jiangsu and 1 other locations) |
| Trial ID | NCT06730334 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate disease activity and treatment response in patients with psoriatic arthritis (PsA) using Power Doppler ultrasonography (PDUS). By employing this non-invasive imaging technology, the study will investigate various clinical features of PsA, including skin, nail, and joint involvement. Participants will be monitored for their compliance with treatment plans and scheduled visits, while their disease activity and potential bone destruction will be assessed based on ultrasonography findings.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with psoriatic arthritis according to the CASPAR criteria.
Not a fit: Patients with a history of other types of arthritis or those with acute or chronic infectious diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of psoriatic arthritis and improve monitoring and treatment strategies for patients.
How similar studies have performed: While the use of PDUS in assessing psoriatic arthritis is established, this specific approach in a prospective observational format may provide novel insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * PsA patients as defined by CASPAR criteria * Patients must be able to comply with the visit schedule, treatment plan, laboratory tests and other study procedures * Patients must be given informed consent Exclusion Criteria: * History of other arthritis within the last 12 months * Concomitant disease with acute or chronic infectious diseases * Pregnancy or laction * Poorly tolerated with venipuncture required for blood sampling during the study
Where this trial is running
Nanjing, Jiangsu and 1 other locations
- Department of Rheumatology and Immunology, Jiangsu Province Hospital — Nanjing, Jiangsu, China (Recruiting)
- Jiangsu Province Hospital — Nanjing, Jiangsu, China (Recruiting)
Study contacts
- Study coordinator: Rui Rui LIU, MD
- Email: liurui_nanjing@163.com
- Phone: +86 15951871668
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.