Understanding how different traits and genes affect treatment responses in psoriatic arthritis
Official title: Association of Phenotypes and Genotype with Treatment Response in Psoriatic Arthritis
Funded at Vanderbilt University Medical Center · NIH-10888391 · Data updated 2026-11-12
This study is looking at how different traits and genes in people with psoriatic arthritis can affect how well treatments work for them, so we can find better, personalized options for managing their condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | July 14, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $163,358 |
| NIH project number | 5K23AR082990-02 |
| Project ID | NIH-10888391 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with psoriatic arthritis who are seeking treatment options.
✕Less likely to help
Patients with psoriatic arthritis who are not currently seeking treatment or those with other overlapping conditions may not benefit from this research.
What this research studies
This research investigates how various clinical traits and genetic factors influence the effectiveness of treatments for patients with psoriatic arthritis (PsA). By analyzing real-world data from two unique patient groups, the study aims to identify specific PsA phenotypes and their correlation with treatment outcomes. The goal is to develop personalized treatment strategies by predicting which patients are likely to respond well to specific therapies. This approach utilizes advanced statistical methods and bioinformatics to enhance the understanding of PsA treatment responses.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment plans for patients with psoriatic arthritis.
How similar studies have gone: Previous research has shown promise in using genetic and clinical data to tailor treatments for chronic conditions, indicating a potential for success in this approach.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Karmacharya, Paras — Vanderbilt University Medical Center
- Study coordinator: Karmacharya, Paras
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.