Educational tool for melanoma patients with autoimmune diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates an educational tool designed for patients with melanoma and pre-existing autoimmune diseases who are candidates for immune checkpoint inhibitors. Participants will navigate the tool and provide feedback on its usability, design, and content. The study aims to assess the acceptability of the tool and its feasibility in real-world settings, including patient recruitment and consent rates. Data collected will be used to enhance educational materials that assist patients in making informed treatment decisions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of melanoma
* Diagnosis of pre-existing autoimmune disease

  * Inflammatory bowel disease

    * Diagnosis of Crohn's disease or ulcerative colitis by a gastroenterologist
    * For ulcerative colitis, proof of chronic changes over time (i.e., 6 months) and signs of inflammation histologically
    * Treatment with aminosalicylates, corticosteroids, thiopurines, or immune modifiers (e.g., calcineurin inhibitors, methotrexate, adhesion molecule antagonists)
  * Rheumatoid arthritis

    * Diagnosis of rheumatoid arthritis by a rheumatologist
    * Treatment with traditional disease-modifying antirheumatic drugs (e.g., methotrexate, sulfasalazine, hydroxychloroquine) or targeted therapy
  * Systemic lupus erythematosus

    * Diagnosis of systemic lupus erythematosus by a rheumatologist
  * Psoriasis

    * Diagnosis of psoriasis by a dermatologist
    * Treatment with corticosteroids, vitamin D analogs, anthralin, topical retinoids, calcineurin inhibitors, salicylic acid, coal tar, or moisturizers; light therapy, including sunlight, ultraviolet B (UVB) phototherapy, narrowband UVB therapy, Goeckerman therapy, photochemotherapy, excimer laser, or pulsed dye laser; or systemic medications, including retinoids, methotrexate, cyclosporine, hydroxyurea, or thioguanine or targeted therapies
  * Spondyloarthropathies

    * Diagnosis of ankylosing spondylitis, reactive arthritis, psoriatic arthritis, or enteropathic arthritis/spondylitis by a rheumatologist
    * Treatment with disease-modifying antirheumatic drugs (e.g., sulfasalazine) or targeted therapy
* Age of 18 years or older
* Patients whose physicians had recommended they begin using any of the currently available immune checkpoint inhibitors or people who are in the midst of or have already made the decision on whether or not start an immune checkpoint inhibitor
* E-mail access and computer with Internet access or telephone
* Ability to communicate in English or Spanish
* CLINICIAN
* Prescribed immune checkpoint inhibitors
* Are providing care for patients with melanoma
* In the clinics at MD Anderson

Where it's running

• M D Anderson Cancer Center
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Angeles Lopez-Olivo — M.D. Anderson Cancer Center
• Study coordinator: Angeles Lopez-Olivo
• Email: amlopezo@mdanderson.org
• Phone: 713-792-9175

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.