Investigating how sleep quality affects inflammation and disease activity in psoriatic arthritis.
Official title: Longitudinal relationships among sleep health, systemic inflammation, and disease activity in psoriatic arthritis
Funded at Brigham and Women's Hospital · NIH-10864337 · Data updated 2026-11-12
This study is looking at how sleep quality affects people with psoriatic arthritis and how their condition might also impact their sleep, so if you have psoriatic arthritis, your experiences could help us understand this connection better over the next year!
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 13, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $173,880 |
| NIH project number | 1K23AR084074-01 |
| Project ID | NIH-10864337 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have been diagnosed with psoriatic arthritis.
✕Less likely to help
Patients who do not have psoriatic arthritis or those under 21 years old may not benefit from this research.
What this research studies
This research focuses on understanding the relationship between sleep health, systemic inflammation, and disease activity in individuals with psoriatic arthritis (PsA). Over a 12-month period, participants will provide both objective data through actigraphy and subjective data via sleep diaries and questionnaires. The study aims to explore how poor sleep quality may hinder the achievement of minimal disease activity and how high disease activity may negatively impact sleep quality, with systemic inflammation acting as a potential mediator in these interactions.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that enhance sleep quality and reduce disease activity in patients with psoriatic arthritis.
How similar studies have gone: Previous research has indicated a significant relationship between sleep quality and disease activity in chronic inflammatory conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Perez Chada, Lourdes — Brigham and Women's Hospital
- Study coordinator: Perez Chada, Lourdes
Related research
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This project aims to find better ways to track how well treatments work for people with early psoriatic arthritis by using at-home RNA samples and smartphone data.
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Understanding spinal inflammation in axial psoriatic arthritis
This study is looking at how inflammation affects the spine in people with axial psoriatic arthritis, using special imaging techniques to get a clearer picture of what's happening, which could help doctors diagnose and treat this condition better.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.