Precision monitoring of Psoriatic Arthritis treatment using at-home RNA sampling and smartphone data
Official title: Precision Monitoring of Treatment Response in Early Psoriatic Arthritis: Integrating at-Home RNA Microsampling into Ongoing, Remote, Smart Phone-Based, Digital Data Capturing
Funded at New York University School of Medicine · NIH-11374491 · Data updated 2026-11-12
A new study will track how Psoriatic Arthritis patients respond to TNF-inhibitor therapy using at-home RNA sampling and a remote smartphone app to collect data.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | June 15, 2024 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $391,846 |
| NIH project number | 5R01AR084274-03 |
| Project ID | NIH-11374491 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (21+ years) with Psoriatic Arthritis who are receiving TNF-inhibitor therapy and have access to a smartphone.
✕Less likely to help
Patients not using TNF inhibitors or without access to at-home sampling and smartphone data collection may not benefit.
What this research studies
If you have Psoriatic Arthritis and are starting or continuing TNF-inhibitor therapy, this study will use simple at-home RNA tests along with a smartphone app to monitor treatment response over time. Researchers will combine these RNA measurements with digital health data to look for patterns that predict who benefits from therapy. The goal is to move toward personalized treatment decisions based on real-time information from patients at home. Participation would involve remote data collection and periodic guidance from the study team through digital tools.
Why it matters
Potential benefit: If successful, the approach could enable quicker, more precise adjustments to therapy, potentially improving outcomes and reducing unnecessary exposure to ineffective treatments.
How similar studies have gone: Prior work suggests that digital monitoring and biomarkers can help tailor treatments, but this specific at-home RNA microsampling approach in PsA is being tested.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Scher, Jose U. — New York University School of Medicine
- Study coordinator: Scher, Jose U.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.