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Postoperative Analgesia clinical trials and research

• 24Clinical trials
• 1New in 30 days
• 5Countries

Newest Postoperative Analgesia clinical trials

All recruiting trials (24)

• Gastrocnemius plane block for foot and ankle surgery

  This study tests whether a gastrocnemius plane block can reduce pain after foot and ankle surgery and lessen the use of opioid pain medicines in adults.

  Recruiting Cairo University · Cairo, Governorate · NCT07877974

• Quadroiliac Plane Block vs Transmuscular Quadratus Lumborum Block for Hip Replacement Pain

  This study tests whether the Quadroiliac Plane Block provides better postoperative pain relief and lower opioid use than the transmuscular quadratus lumborum block after total hip arthroplasty conducted under spinal anesthesia.

  Recruiting Tanta University · Tanta, El-Gharbia · NCT07815145

• Deep iliacus plane block vs transmuscular quadratus lumborum block for hip surgery pain relief

  This study tests whether the deep iliacus plane block provides better pain relief and recovery than the transmuscular quadratus lumborum block after total hip replacement.

  Recruiting Tanta University · Tanta, El-Gharbia · NCT07798830

• PIFPB-based blocks to aid pain relief after cardiac surgery

  This observational study tests whether combining a pectoral-intercostal fascial plane block with either a recto-intercostal fascial plane block or a rectus sheath block can improve postoperative pain control for adults undergoing elective cardiac surgery.

  Recruiting Antalya Health Sciences University · Antalya · NCT07622823

• Bilateral ESPB versus OSTAPB for postoperative pain after colorectal surgery

  This study tests whether, after open colorectal surgery, an ultrasound-guided bilateral erector spinae plane block works better or the bilateral OSTAP block works better for controlling pain.

  Recruiting Cairo University · Cairo · NCT07602452

• Comparing three ultrasound-guided nerve blocks to reduce pain after video-assisted thoracic surgery

  This trial will try three ultrasound-guided regional blocks — paravertebral, intertransverse process, and erector spinae plane — to see which best lowers opioid use and pain after elective VATS in adults.

  Recruiting Antalya Training and Research Hospital · Antalya, Muratpaşa · NCT07578545

• Dexmedetomidine or Clonidine added to spinal anesthesia for cesarean delivery

  This study tests whether adding dexmedetomidine or clonidine to spinal anesthesia for cesarean delivery improves intraoperative comfort and analgesia.

  Recruiting Phase 4 Columbia University · New York, New York · NCT07567495

• PENG versus Deep Iliacus Plane block for pain relief in intertrochanteric femur fractures

  This study will see if PENG or Deep Iliacus Plane nerve blocks give better pain relief and make positioning for spinal anesthesia easier for adults having surgery for intertrochanteric hip fractures.

  Recruiting Erzincan Binali Yildirim Universitesi · Erzincan, Merkez/Türkiye · NCT07513740

• Oliceridine vs Sufentanil for postoperative nausea after CPA surgery

  This trial tests whether using oliceridine for patient-controlled IV pain relief reduces nausea after cerebellopontine angle surgery compared with sufentanil.

  Recruiting Xuanwu Hospital, Beijing · Beijing · NCT07479446

• Serratus posterior superior intercostal plane block for pain control after off-pump minimally invasive CABG

  This trial will test whether an ultrasound-guided serratus posterior superior intercostal plane block with bupivacaine reduces postoperative pain in adults having elective off-pump minimally invasive coronary artery bypass grafting.

  Recruiting Kartal Kosuyolu High Speciality Training and Research Hospital · Istanbul · NCT07412522

• Erector spinae versus lateral transversus abdominis plane block for pain after open appendectomy

  This study will test whether an erector spinae plane block or a lateral TAP block gives better pain relief for adults having open appendectomy.

  Recruiting Cairo University · Cairo, Cairo Governorate · NCT07351253

• Anrikefon Injection for Postoperative Pain After Laparoscopic Gastrectomy in Gastric Cancer

  This trial tests whether Anrikefon given by IV can reduce pain after totally laparoscopic distal gastrectomy for gastric cancer.

  Recruiting Phase 2 Tianjin Medical University Cancer Institute and Hospital · Tianjin, Tianjin Municipality · NCT07330063

• Abdominal nerve block versus thoracic epidural for pain after major abdominal cancer surgery

  This will test whether combined subcostal and lateral transversus abdominis plane (TAP) blocks provide pain relief comparable to thoracic epidural anesthesia for adults having major abdominal cancer surgery.

  Recruiting Assiut University · Asyut · NCT07273136

• Erector spinae plane block for pain after laparoscopic abdominal surgery

  This will test whether giving an erector spinae plane block reduces pain and 24-hour opioid use for adults having laparoscopic abdominal surgery.

  Recruiting Assiut University · Asyut · NCT07272577

• IV pain medicine, thoracic epidural, and erector spinae plane block for long-term pain after open-heart surgery

  This study will compare three common pain-control approaches—IV pain medicines, thoracic epidural, and erector spinae plane block—to see if one lowers chronic pain three months after open-heart surgery.

  Recruiting Karadeniz Technical University · Trabzon, Trabzon · NCT07257744

• HRS-2129 for managing pain after abdominal surgery

  This trial will test whether HRS-2129 tablets provide better pain relief than tramadol for adults after abdominal surgery.

  Recruiting at 2 sites Phase 2/3 Shandong Suncadia Medicine Co., Ltd. · Zhengzhou, Henan and 1 other locations · NCT07185594

• Dexamethasone versus magnesium added to bupivacaine for erector spinae plane block after elective cesarean

  This study will test whether adding dexamethasone or magnesium sulfate to bupivacaine in an erector spinae plane block gives better pain relief after elective cesarean under spinal anesthesia.

  Recruiting Cairo University · Cairo · NCT07139522

• Lidocaine plus dexmedetomidine during laparoscopic bariatric surgery to reduce pain, inflammation, and oxidative stress

  This trial will try giving an intravenous combination of lidocaine and dexmedetomidine during laparoscopic bariatric surgery in adults with obesity to see if it lowers pain, inflammation, and oxidative stress after surgery.

  Recruiting at 2 sites Phase 4 Instituto Mexicano del Seguro Social · Mexico City, Mexico City and 1 other locations · NCT07073846

• Combining Ketamine and Magnesium for Pain Relief After Nose Surgery

  This study is testing whether combining ketamine and magnesium during nose surgery can help reduce pain and lower the need for opioids afterward.

  Recruiting Ain Shams University · Cairo · NCT06966518

• Comparing two nerve block techniques for pain relief after hip surgery

  This study is testing which of two nerve block techniques helps people recover with less pain and fewer opioids after hip surgery.

  Recruiting Başakşehir Çam & Sakura City Hospital · Istanbul, Türki̇ye · NCT06821516

• Using Methylene Blue to Improve Recovery After Hemorrhoid Surgery

  This study tests if using Methylene Blue can help people recover better after hemorrhoid surgery by looking at their pain levels and overall well-being.

  Recruiting at 3 sites Qilu Hospital of Shandong University · Heze, Shandong and 2 other locations · NCT06747195

• Using Oliceridine for Pain Relief After Surgery

  This study is testing different doses of a new pain medication called oliceridine to see how well it helps people manage pain after upper abdominal surgery compared to morphine.

  Recruiting Tongji Hospital · Wuhan, Hubei · NCT06409689

• Liposomal versus standard bupivacaine for thoracic paravertebral block after thoracoscopic lobectomy

  This test checks whether adding long-acting liposomal bupivacaine to standard bupivacaine for thoracic paravertebral nerve blocks reduces pain after thoracoscopic lobectomy in adults.

  Recruiting Phase 4 Qianfoshan Hospital · Jinan, Shandong · NCT06165991

• Esketamine dose levels combined with dexmedetomidine to reduce pain after scoliosis correction

  This study will test whether different doses of esketamine given with dexmedetomidine and opioids can reduce immediate postoperative pain and lower the chance of chronic postsurgical pain in adults having scoliosis correction.

  Recruiting Phase 4 Peking University First Hospital · Beijing, Beijing Municipality · NCT06087510

Related topics

Quick answers

How many Postoperative Analgesia clinical trials are recruiting right now?

24, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in Egypt (9 trials), China (7 trials), Turkey (Türkiye) (6 trials), Mexico (1 trial), United States (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 4, Phase 2/3: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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