Bilateral ESPB versus OSTAPB for postoperative pain after colorectal surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional trial compares two ultrasound-guided regional anesthesia techniques in adults undergoing open colorectal surgery. It evaluates postoperative analgesia provided by bilateral erector spinae plane blocks versus bilateral oblique subcostal transversus abdominis plane blocks. Eligible participants are 18 to 75 years old, ASA II-III, and not at high risk for infection, coagulopathy, or opioid-related complications. The study is led by Cairo University, with sites at Cairo University, and does not list additional collaborators. Outcomes focus on pain control and analgesic requirements after surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 to 75 years old.
* Both sexes.
* American Society of Anesthesiologists (ASA) physical status II-III.
* Scheduled for open colorectal surgery under general anesthesia.

Exclusion Criteria:

* History of opioid abuse.
* Chronic opioid consumption.
* Body mass index (BMI) ≥ 35 kg/m2.
* Severe cardiac insufficiency, defined as New York Heart Association (NYHA) class III or IV heart failure.
* Renal failure, defined as an estimated glomerular filtration rate (eGFR) \< 30 mL/min/1.73 m².
* Hepatic encephalopathy.
* Having a skin infection at or near the puncture site.
* Coagulopathy, defined as platelet count \< 100,000/mm³, INR \> 1.5, or use of anticoagulant therapy that could not be withheld.
* Allergy to drugs used in the study.
* History of previous or recurrent laparoscopic cholecystectomy procedures.

Where it's running

• Cairo University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Mohammed M Alarousy, MSc
• Email: mohammedalarousy0@gmail.com
• Phone: 00201149404478

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.