Quadroiliac Plane Block vs Transmuscular Quadratus Lumborum Block for Hip Replacement Pain
Official title: Quadroiliac Plane Block Versus Transmuscular Quadratus Lumborum Block for Postoperative Analgesia After Total Hip Arthroplasty: A Randomized Clinical Trial
Run by Tanta University · NCT07815145 · Data updated 2026-11-12
This study tests whether the Quadroiliac Plane Block provides better postoperative pain relief and lower opioid use than the transmuscular quadratus lumborum block after total hip arthroplasty conducted under spinal anesthesia.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta, El-Gharbia) |
| Status | Recruiting |
| Started | September 12, 2026 |
| Main results expected | February 1, 2027 |
| Study ends | February 1, 2027 |
| Registry record updated | September 15, 2026 |
| Trial ID | NCT07815145 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults 18–75 undergoing elective unilateral THA under spinal anesthesia, without allergy to local anesthetics or contraindications to regional blocks.
✕Probably not a fit
Patients with BMI >40, chronic opioid use, significant organ dysfunction, infection at the injection site, or contraindications to regional anesthesia may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares two ultrasound-guided regional anesthesia techniques in adults undergoing elective unilateral total hip arthroplasty with spinal anesthesia. It will look at postoperative analgesia, opioid consumption, motor function preservation, and overall recovery quality to see which block offers superior pain control and faster recovery. Participants are adults 18 to 75 with ASA I–III and no contraindications to regional anesthesia. The QIPB is a newer approach targeting hip-related sensory innervation, while the QLB blocks similar regions via a different fascial plane. The trial is conducted at Tanta University with local procedures and standard perioperative care.
Why it matters
Potential benefit: If successful, patients could experience better pain relief after hip replacement with less opioid use and quicker recovery.
How similar studies have gone: Prior studies in regional anesthesia for hip surgery suggest some blocks provide effective analgesia; this head-to-head comparison explores newer QIPB against an established technique.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18-75 years. * Both sexes. * American Society of Anesthesiologists (ASA) classification I-III. * Scheduled for elective primary unilateral total hip arthroplasty under spinal anesthesia. Exclusion Criteria: * Allergy to local anesthetics. * Infection at the injection site. * Coagulopathy or bleeding disorders. * Neuromuscular disorders. * Chronic opioid use or dependence. * Body mass index (BMI) \> 40 kg/m². * Severe cardiac, hepatic, renal, or respiratory dysfunction. * Contraindication to regional anesthesia.
Where it's running
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Tanta University
Tanta, El-Gharbia, Egypt Recruiting
Study contacts
- Study coordinator: Mohammed S Elsharkawy, MD
- Email: mselsharkawy@med.tanta.edu.eg
- Phone: 00201148207870
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.