Using Methylene Blue to Improve Recovery After Hemorrhoid Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the effects of Methylene Blue (MB) on the quality of recovery in patients undergoing hemorrhoidectomy. It utilizes the Quality of Recovery (QOR-15) score to objectively measure various aspects of patient recovery, including pain management and overall well-being. The study focuses on patients diagnosed with grade III/IV mixed hemorrhoids who are treated under spinal anesthesia. Previous research has indicated that MB may provide temporary pain relief by disrupting anal sensory nerve terminals, making this an important area of exploration for postoperative care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosed with mixed hemorrhoids, grade III/ IV hemorrhoids (Goligher's classification), and underwent hemorrhoidectomy under spinal anesthesia; and
* Aged between 18 and 65 years; and
* ASA I or II.

Exclusion Criteria:

* Patients who experienced any ill-effects from previous use of MB or other medications in the protocol (ketorolac, ropivacaine); or
* Patients with diabetes; or
* Alcohol or other addictive drug dependence; or
* Illiteracy, combined with mental system or severe mental illness that prevented completion of the assessment; or
* Patients who are pregnant or breast-feeding; or
* Aspirin and analgesic drugs taken within 2 weeks before surgery; or
* Patients taking selective serotonin reuptake inhibitors (SSRIs); or
* Concurrent additional anorectal diseases (e.g., perianal abscess, anal fistula, fissures, anal incontinence); or
* Patients who are participating in other clinical trials and have not reached the endpoint.

Where it's running

• Heze Hospital of Traditional Chinese Medicine
  Heze, Shandong, China Recruiting
• Qilu hospital of Shandong University
  Jinan, Shandong, China Recruiting
• Weifang People's Hospital
  Weifang, Shandong, China Recruiting

Study contacts

• Study coordinator: Liang Li, MD
• Email: liliang675@126.com
• Phone: +8618560083822

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Gastrocnemius plane block for foot and ankle surgery

  This study tests whether a gastrocnemius plane block can reduce pain after foot and ankle surgery and lessen the use of opioid pain medicines in adults.

  Recruiting Cairo University · Cairo, Governorate · NCT07877974

• Electronic bidets after anal surgery vs water rinsing

  A small study tests whether using an electronic bidet after anal fistula or hemorrhoid surgery helps patients more than standard water rinsing.

  Recruiting Universitair Ziekenhuis Brussel · Brussels · NCT07874711

• Quadroiliac Plane Block vs Transmuscular Quadratus Lumborum Block for Hip Replacement Pain

  This study tests whether the Quadroiliac Plane Block provides better postoperative pain relief and lower opioid use than the transmuscular quadratus lumborum block after total hip arthroplasty conducted under spinal anesthesia.

  Recruiting Tanta University · Tanta, El-Gharbia · NCT07815145

• Deep iliacus plane block vs transmuscular quadratus lumborum block for hip surgery pain relief

  This study tests whether the deep iliacus plane block provides better pain relief and recovery than the transmuscular quadratus lumborum block after total hip replacement.

  Recruiting Tanta University · Tanta, El-Gharbia · NCT07798830

• Minimally Invasive Closed Hemorrhoidectomy for Grade III Hemorrhoids

  This study tests a minimally invasive, closed hemorrhoidectomy approach for adults with Grade III hemorrhoids to see if it offers good outcomes with less pain and quicker healing.

  Recruiting Hospital Son Llatzer · Palma de Mallorca · NCT07695649

• PIFPB-based blocks to aid pain relief after cardiac surgery

  This observational study tests whether combining a pectoral-intercostal fascial plane block with either a recto-intercostal fascial plane block or a rectus sheath block can improve postoperative pain control for adults undergoing elective cardiac surgery.

  Recruiting Antalya Health Sciences University · Antalya · NCT07622823

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.