Gastrocnemius plane block for foot and ankle surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study investigates ultrasound-guided gastrocnemius plane block using bupivacaine to provide postoperative analgesia for elective foot and ankle procedures. It will measure how long the block lasts, how much rescue analgesia is needed in the first 24 hours, and pain levels at multiple time points after surgery. The trial will also monitor for block-related complications such as motor weakness, vascular puncture, nerve injury, or local anesthetic toxicity. The hypothesis is that GPB will lower pain scores and reduce opioid consumption compared with standard analgesic management. Participants are adults aged 18-65 undergoing specified foot and ankle surgeries, receiving 30 mL of 0.25% bupivacaine via ultrasound guidance.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Elective foot and ankle surgeries, including procedures for fractures of the fibula, tibia-fibula, metatarsal, or calcaneus, as well as corrective surgery for hallux valgus;
* Aged 18- 65 years
* BMI 18-28 kg/m2
* ASA Ⅰ-Ⅲ.

Exclusion Criteria:

* Puncture site infection
* Abnormal coagulation function: international normalized ratio (INR) \> 1.5; platelet count \< 50×109/L
* Local anaesthesia allergy
* Unstable coronary syndrome (e.g., recent myocardial infarction within 3 months);
* Severe cardiopulmonary disease: heart failure (NYHA, functional class III or IV)
* Severe pulmonary disease (e.g., chronic obstructive pulmonary disease with FEV1 \< 50% of predicted, or requiring home oxygen therapy)
* Liver insufficiency: liver disease (Child- Pugh class B or C) or elevated liver enzymes (ALT or AST) \> 3 times the upper limit of normal;
* Renal insufficiency renal impairment (estimated glomerular filtration rate, eGFR\<30 mL/min/1.73m2) or requiring renal replacement therapy
* Long-term preoperative use of sedative and analgesic drugs;
* Communication disorders
* History of chronic pain.
* Operative time \> 3 h.

Where it's running

• Cairo university , faculty of medicine
  Cairo, Governorate, Egypt Recruiting

Study contacts

• Principal investigator: Nagy Malak, MD — Cairo University
• Study coordinator: Nagy Malak, MD
• Email: nagymalak@kasralainy.edu.eg
• Phone: 01552480258

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.