Comparing two nerve block techniques for pain relief after hip surgery
Official title: Comparison of Analgesic Effectiveness Between Pericapsular Nerve Group (PENG) Block and Lumbar Erector Spinae Plane Block in Patients Undergoing Total Hip Arthroplasty With Spinal Anesthesia: a Randomized Controlled Trial
Run by Başakşehir Çam & Sakura City Hospital · NCT06821516 · Data updated 2026-11-12
This study is testing which of two nerve block techniques helps people recover with less pain and fewer opioids after hip surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 52 (estimated) |
| Sponsor | Başakşehir Çam & Sakura City Hospital Government |
| Locations | 1 site (Istanbul, Türki̇ye) |
| Status | Recruiting |
| Started | January 21, 2025 |
| Main results expected | March 1, 2026 |
| Study ends | June 1, 2026 |
| Registry record updated | May 7, 2026 |
| Trial ID | NCT06821516 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old who are scheduled for total hip arthroplasty and have an ASA score of I-III.
✕Probably not a fit
Patients with ASA scores IV-V, chronic pain conditions, or those unable to cooperate with postoperative follow-up may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective randomized comparative study evaluates the effectiveness of two nerve block techniques, the Pericapsular Nerve Group (PENG) block and the Lumbar Erector Spinae Plane (L-ESP) block, in managing postoperative pain for patients undergoing total hip arthroplasty under spinal anesthesia. Participants over 18 years old will be monitored for pain scores, opioid consumption, and satisfaction for 24 hours post-surgery. The study aims to determine which nerve block provides superior analgesia, reduces opioid dependence, and enhances recovery outcomes.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for hip surgery patients, reducing opioid use and enhancing recovery.
How similar studies have gone: Previous studies have indicated the effectiveness of peripheral nerve blocks in postoperative pain management, suggesting potential success for this comparative approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Voluntary willingness to participate in the study. * Patients who will undergo Total Hip Arthroplasty surgery. * Patients aged over 18 years. * ASA score I-II-III. * Patients who are fully oriented and can cooperate. Exclusion Criteria: * ASA score IV-V. * Patients who refuse to participate in the study. * Patients under 18 years of age. * Presence of active infection in the area to be operated on. * Chronic pain and continuous analgesic use. * Patients with coagulation disorders. * Patients who cannot cooperate with postoperative pain follow-up. * Patients with allergies to local anesthetic agents. * Presence of neuropathy or myopathy in the operated extremity.
Where it's running
-
Basaksehir Çam Ve Sakura City Hospital
Istanbul, Türki̇ye, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Muzaffer Gencer
- Email: aberkaysune@gmail.com
- Phone: +905059436459
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
SPSIP Block to Help Pain After Breast Reduction Surgery
A randomized trial tests whether adding an ultrasound-guided SPSIP block can lower opioid use in the first 24 hours after bilateral breast reduction surgery.
-
Bupivacaine plus lidocaine versus bupivacaine alone for ultrasound-guided popliteal sciatic nerve block
This trial will test whether adding lidocaine to bupivacaine gives faster numbness and longer-lasting pain relief for adults having below-knee (foot or ankle) surgery with an ultrasound-guided popliteal sciatic nerve block.
-
PENG block plus local infiltration analgesia for anterior-approach hip replacement
This test sees if a motor-sparing PENG block combined with local infiltration around the hip controls pain as well as spinal anesthesia for adults having anterior‑approach hip replacement.
-
Erector spinae plane block for managing pain after breast cancer surgery
This study is testing if a special nerve block combined with a medication can help reduce pain and improve recovery for women after breast cancer surgery.
-
Gastrocnemius plane block for foot and ankle surgery
This study tests whether a gastrocnemius plane block can reduce pain after foot and ankle surgery and lessen the use of opioid pain medicines in adults.
-
Suzetrigine for pain relief after knee replacement
This trial tests whether suzetrigine can reduce opioid use after a total knee replacement compared with placebo.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.