Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Comparing two nerve block techniques for pain relief after hip surgery

Official title: Comparison of Analgesic Effectiveness Between Pericapsular Nerve Group (PENG) Block and Lumbar Erector Spinae Plane Block in Patients Undergoing Total Hip Arthroplasty With Spinal Anesthesia: a Randomized Controlled Trial

Run by Başakşehir Çam & Sakura City Hospital · NCT06821516 · Data updated 2026-11-12

This study is testing which of two nerve block techniques helps people recover with less pain and fewer opioids after hip surgery.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment52 (estimated)
SponsorBaşakşehir Çam & Sakura City Hospital
Government
Locations1 site (Istanbul, Türki̇ye)
StatusRecruiting
StartedJanuary 21, 2025
Main results expectedMarch 1, 2026
Study endsJune 1, 2026
Registry record updatedMay 7, 2026
Trial IDNCT06821516 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 years old who are scheduled for total hip arthroplasty and have an ASA score of I-III.

Probably not a fit

Patients with ASA scores IV-V, chronic pain conditions, or those unable to cooperate with postoperative follow-up may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective randomized comparative study evaluates the effectiveness of two nerve block techniques, the Pericapsular Nerve Group (PENG) block and the Lumbar Erector Spinae Plane (L-ESP) block, in managing postoperative pain for patients undergoing total hip arthroplasty under spinal anesthesia. Participants over 18 years old will be monitored for pain scores, opioid consumption, and satisfaction for 24 hours post-surgery. The study aims to determine which nerve block provides superior analgesia, reduces opioid dependence, and enhances recovery outcomes.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for hip surgery patients, reducing opioid use and enhancing recovery.

How similar studies have gone: Previous studies have indicated the effectiveness of peripheral nerve blocks in postoperative pain management, suggesting potential success for this comparative approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Voluntary willingness to participate in the study.
* Patients who will undergo Total Hip Arthroplasty surgery.
* Patients aged over 18 years.
* ASA score I-II-III.
* Patients who are fully oriented and can cooperate.

Exclusion Criteria:

* ASA score IV-V.
* Patients who refuse to participate in the study.
* Patients under 18 years of age.
* Presence of active infection in the area to be operated on.
* Chronic pain and continuous analgesic use.
* Patients with coagulation disorders.
* Patients who cannot cooperate with postoperative pain follow-up.
* Patients with allergies to local anesthetic agents.
* Presence of neuropathy or myopathy in the operated extremity.

Where it's running

  • Basaksehir Çam Ve Sakura City Hospital
    Istanbul, Türki̇ye, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.