Screening siblings of children with autism for neurodevelopmental disorders

Screening for Neurodevelopmental Disorders in Siblings of Children With Autism Diagnosed in Tertiary Centers

University Hospital, Montpellier · NCT05512637

This study is testing a new way to check if siblings of children with autism have any neurodevelopmental disorders to better understand their needs.

Quick facts

Study typeObservational
Enrollment384 (estimated)
Ages2 Years to 16 Years
SexAll
SponsorUniversity Hospital, Montpellier (other)
Locations1 site (Montpellier)
Trial IDNCT05512637 on ClinicalTrials.gov

What this trial studies

This observational study focuses on screening siblings of children diagnosed with Autism Spectrum Disorder (ASD) for neurodevelopmental disorders (NDD). It employs a multi-stage screening process to estimate the prevalence of NDD among these siblings and evaluates the feasibility and acceptability of a standardized screening procedure. The study aims to improve understanding of the developmental needs of these siblings, which are often overlooked in routine practice.

Who should consider this trial

Good fit: Ideal candidates for this study are siblings aged 2 to 16 years of children diagnosed with autism, living in the Occitanie region of France.

Not a fit: Patients who may not benefit from this study include adopted siblings or those who do not speak French.

Why it matters

Potential benefit: If successful, this study could lead to earlier identification and intervention for neurodevelopmental disorders in siblings of children with autism.

How similar studies have performed: Other studies have indicated the importance of screening siblings of children with autism, suggesting that this approach could yield valuable insights and improvements in developmental surveillance.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Step 1: Brothers or sisters (including stepsisters and brothers); aged between 2 and 16 years; living in Occitanie; informed and express consent of parents ; affiliated to social security.
* Step 2: step 1 positive screening or parental concerns for child's development ; parental signed informed consent.

Exclusion Criteria:

* Parents (or child) refusal to participate; adopted brother or sister. Do not speak French

Where this trial is running

Montpellier

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Autism Spectrum Disorder, Siblings, Neurodevelopmental Disorders, Screening

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.