Understanding motor behavior in high-risk infants
Official title: Neuro-biomechanical Aspects Determining the Motor Behavior in Infants With High-risk of Neuromotor Impairments
Run by University Hospital, Geneva · NCT06111898 · Data updated 2026-11-12
This study is trying to understand how movement and muscle development in high-risk infants, like those born early or with brain injuries, compare to typically developing infants to help find better ways to support their growth.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 35 Weeks to 1 Year |
| Sex | All |
| Enrollment | 348 (estimated) |
| Sponsor | University Hospital, Geneva Academic / other |
| Locations | 1 site (Geneva) |
| Status | Recruiting |
| Started | October 10, 2023 |
| Main results expected | March 31, 2026 |
| Study ends | December 31, 2027 |
| Registry record updated | November 15, 2023 |
| Trial ID | NCT06111898 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include infants born before or at 28 weeks of gestation, those with brain injuries, or term infants diagnosed with asphyxia or neonatal stroke.
✕Probably not a fit
Patients with genetic syndromes or lower limb pathologies may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project investigates the motor development, muscle growth, and muscle activity in high-risk infants, particularly those born prematurely or with brain injuries. Using advanced techniques like 3D freehand ultrasound and electromyography, the study aims to identify the neuro-biomechanical factors that influence motor behavior during the first year of life. By comparing high-risk infants with typically developing infants, the research seeks to establish a comprehensive assessment tool for early diagnosis and intervention strategies.
Why it matters
Potential benefit: If successful, this study could lead to improved early diagnosis and targeted therapies for high-risk infants, enhancing their long-term neurodevelopmental outcomes.
How similar studies have gone: While this approach is innovative, similar studies have shown promise in understanding neurodevelopmental outcomes in high-risk populations.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion \& exclusion criteria for group of high-risk infants: * Infants born before or at 28 weeks of gestation * Infants born after 28 weeks of gestation and with brain injury. * A term birth with the clinical diagnosis of asphyxia (ischemic event with hypothermia) or neonatal stroke * Exclusion in case of genetic syndrome, or lower limb pathology (e.g. spina bifida) Inclusion \& exclusion criteria for group of typically developing children: * Born at a gestational age above 37 weeks * Birth weight between P10 and P90 * Head circumference between P10 and P90 * Ph \>7.1 * Exclusion in case of genetic syndrome, lower limb pathology and/or brain malformations
Where it's running
-
University Hospitals Geneva
Geneva, Switzerland Recruiting
Study contacts
- Study coordinator: Nathalie De Beukelaer, PhD
- Email: nathalie.debeukelaer@unige.ch
- Phone: +41783033552
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.