Understanding how sensory brain signals vary in people with and without neurodevelopmental disorders
Official title: Individual Neurophysiological Sensory Profiles in People With and Without Neurodevelopmental Disorders
Run by University Hospital, Tours · NCT07542977 · Data updated 2026-11-12
This study tests whether people with neurodevelopmental disorders show more variation in brain responses to sensory stimulation than people without these disorders.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 6 Years to 45 Years |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | University Hospital, Tours Academic / other |
| Locations | 1 site (Tours) |
| Status | Recruiting |
| Started | May 7, 2026 |
| Main results expected | July 15, 2026 |
| Study ends | June 15, 2028 |
| Registry record updated | June 16, 2026 |
| Trial ID | NCT07542977 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 6–12 years (children) or 18–45 years (adults) with or without neurodevelopmental disorders, who can undergo EEG recording and complete behavioral assessments.
✕Probably not a fit
Participants whose sensory processing or brain signal variability does not differ from typical ranges may have no direct benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will record EEG and other brain signals while participants experience sensory stimuli, then compare intra-individual variability across groups. Participants will also complete behavioral assessments and questionnaires and engage in at-home perceptual learning training between three in-person visits over up to three months. The goal is to see if brain signal variability relates to learning and behavioral profiles. The study is observational and does not assign a treatment. Eligibility includes adults and children with or without neurodevelopmental disorders, with specific age ranges and diagnostic criteria.
Why it matters
Potential benefit: If successful, findings could improve understanding of sensory processing differences and guide personalized approaches for learning and support.
How similar studies have gone: Previous research has shown measurable neurophysiological differences in sensory processing in some neurodevelopmental disorders, though results vary by modality and population.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Social security affiliation * Free and written informed consent from the participants (Neurotypical Adults, NDD Adults without judicial protective measures), or their tutor or legal representant(s) (other participants) * Age between 6 and 12 years included (Children) or between 18 and 45 years included (Adults) * For NDD participants: NDD diagnosis by a qualified medical professional, according to DSM-4, DSM-5, ICD-10 or ICD-11 criteria Non-inclusion Criteria: * Psychotropic medication perturbing EEG recording * Drugs pertubing peripheral neurophysiological measures * Non-corrected visual or auditory troubles * Known neurological or psychiatric conditions (at the exclusion of NDD for NDD participants) * Epilepsy * Inclusion in another ongoing medical protocol * For Neurotypical participants: NDD diagnosis * For NDD participants: anticipated psychological or physical risk at participating, at the investigator's discretion Exclusion Criteria: * Participants with no data to evaluate Outcome 1
Where it's running
-
Wardak
Tours, France Recruiting
Study contacts
- Study coordinator: Claire WARDAK, Dr
- Email: claire.wardak@univ-tours.fr
- Phone: 02 47 47 97 47
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Understanding brain development in congenital hypothyroidism: comparing affected children, healthy controls, and mild thyroid conditions
This study tests how brain development in children with congenital hypothyroidism compares to similar children without the condition and to kids with a mild thyroid finding.
-
Leopard: using multi-omics to boost genetic diagnosis for neurodevelopmental disorders
This study tests a multi-omics approach to find genetic explanations for neurodevelopmental disorders in people with moderate-to-severe intellectual disability.
-
Melillo Method for kids with behavior and learning challenges
This pilot test will see if the Melillo Method can be feasibly delivered in two Illinois schools to help kids aged 8 and up who have behavioral and learning difficulties.
-
Two-week intensive brain-focused therapy program for children with neurodevelopmental and chromosomal conditions
This program will try a two-week, individualized multimodal neurorehabilitation approach for children about 4–12 years old with neurodevelopmental or chromosomal conditions to see if it improves attention, motor skills, communication, and daily functioning.
-
Social cognition testing for 8–16-year-olds with autism, ADHD, or atypical development
This project will test a multidimensional social-cognition battery in French-speaking 8–16-year-olds with autism, ADHD, or atypical neurodevelopment to see if it better identifies social processing differences.
-
Virtual reality to boost neuroplasticity in children and adolescents
This project will try immersive virtual reality rehabilitation to improve attention, motor skills, social interaction, and quality of life in children and teens aged 8–18 with ADHD, autism, or cerebral palsy.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.