Condition

Intensive Care clinical trials and research

• 10Clinical trials
• 58NIH research projects
• 5Countries

Newest Intensive Care clinical trials

All recruiting trials (10)

• Structured education for families of patients with tracheostomy in the ICU

  This trial tests whether giving a structured education session to family members of ICU patients with tracheostomies can reduce their state anxiety and improve well-being and satisfaction with care.

  Recruiting Giresun University · Giresun, Giresun · NCT07737353

• Improving lung function during chest physiotherapy for patients on mechanical ventilation

  This study is testing if a special breathing technique can help improve lung function in patients on mechanical ventilation by comparing two different ways of supporting their breathing.

  Recruiting Assistance Publique - Hôpitaux de Paris · Créteil · NCT06805357

• Using Remimazolam for Sedation in Patients After Heart Surgery

  This study tests if a new sedative called remimazolam can help heart surgery patients recover better and get off breathing machines faster compared to a standard sedative.

  Recruiting First Affiliated Hospital of Zhejiang University · Hangzhou, Zhejiang · NCT06716840

• AI software predicting acute kidney injury in ICU patients

  This study is testing whether a new AI tool can help doctors predict and prevent kidney problems in ICU patients by alerting them when someone is at high risk.

  Recruiting Huede Healthtech Co., Ltd. · Taichung · NCT06685367

• Mouth assessment tool for adults with oral intubation in intensive care

  This project tries a new checklist nurses can use to check mouth health in adults who are orally intubated in intensive care.

  Recruiting University Hospital, Bordeaux · Angers and 9 other locations · NCT06628440

• Monitoring blood flow and response to fluids in patients on ECMO

  This study is testing different ways to monitor blood flow and heart function in adults receiving VA ECMO treatment to see which methods work best for their care.

  Recruiting Medical University of Vienna · Vienna · NCT06593756

• Testing monitoring methods for patients on ECMO support

  This study is testing different ways to monitor heart function and fluid levels in patients on ECMO support for severe breathing problems to see which methods work best.

  Recruiting Medical University of Vienna · Vienna · NCT06593717

• Understanding immune response in intensive care patients

  This study is trying to see how the immune system responds in intensive care patients after serious injuries or surgeries to find the best ways to boost their immune defense and improve their recovery.

  Recruiting at 2 sites Assistance Publique - Hôpitaux de Paris · Annecy and 6 other locations · NCT06549374

• Predicting rehabilitation outcomes for ICU patients on mechanical ventilation

  This study is trying to see if early rehabilitation can help ICU patients on mechanical ventilation recover better and which patients are most likely to benefit from it.

  Recruiting Wuhan University · Wuhan, Hubei · NCT06532994

• Understanding glucose distribution in severely burned adults

  This study is testing how glucose levels change in severely burned adults during their first four days of treatment to help doctors manage their fluids better and improve recovery.

  Recruiting Phase 2 Centre Hospitalier Régional Metz-Thionville · Metz · NCT06469970

NIH-funded research (newest 40 of 58)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Phthalate Exposure and How It Affects Newborns in the NICU

  This grant looks at how chemicals called phthalates in the NICU environment may affect the health and development of newborns, especially those born prematurely.

  NIH research Feinstein Institute for Medical Research · Manhasset, United States · NIH-11594454

• Pediatric ICU Sedation and Brain Recovery after Injury

  This grant studies how sedation given in the pediatric ICU affects short- and long-term brain recovery in children who have suffered brain injuries.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11528580

• Improving care for opioid use disorder in the ICU

  This project helps hospital staff in intensive care units provide better care for patients with opioid use disorder.

  NIH research Mainehealth · Portland, United States · NIH-11477142

• Ownership of private-equity owned neonatal care and its effect on NICU outcomes

  This project will look at how private-equity ownership of neonatal care groups and hospitals relates to how newborns fare in the NICU, with a focus on U.S. practices.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11416706

• Juggling Work and Family for Parents of Very Preterm Babies

  A study to understand how work and family demands affect parents of very preterm infants and how this shapes their ability to support their baby’s development.

  NIH research Women and Infants Hospital-Rhode Island · Providence, United States · NIH-11413664

• Implementing SDOH screening and referrals in the NICU to support fragile newborns

  A NICU-based program to screen newborns and families for social needs and connect them to services that can improve health and development.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11398100

• Attenuating Depression with Internet CBT to Slow Cognitive Decline in Older ICU Survivors

  A new online cognitive behavioral therapy program is being tested to help older ICU survivors who are experiencing depressive symptoms and may be at risk for cognitive decline.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11397007

• Multisensory care to boost development in preterm babies in the NICU

  A program called SENSE uses gentle touch, sounds, and parent bonding in the NICU to support brain development for very preterm infants and help families stay involved.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11378465

• Sleep, pain, and recovery after pediatric intensive care

  This project explores how pain and sleep problems affect kids after PICU stay and what could help them recover better at home and in school.

  NIH research Oregon Health & Science University · Portland, United States · NIH-11376991

• Improving ICU family meetings: how communication quality affects outcomes

  This project studies how the way doctors and ICU teams talk with family members affects stress, satisfaction, and care for seriously ill patients.

  NIH research Pennsylvania State Univ Hershey Med Ctr · Hershey, United States · NIH-11362176

• Learning Health System in VA ICUs improves care for Veterans

  A VA study will measure how well ICUs use a learning health system to standardize care and improve outcomes for Veterans with life-threatening illnesses.

  NIH research VA Boston Health Care System · Boston, United States · NIH-11348682

• Supporting opioid use disorder care in the ICU with a clinician dashboard and education

  Aimed at improving how ICU teams in MaineHealth identify and treat opioid use disorder, using a clinician dashboard, tailored education, and language processing to standardize care.

  NIH research Mainehealth · Portland, United States · NIH-11334491

• Telehealth ICU recovery program for Alzheimer’s-related memory problems

  A telehealth program helps ICU survivors with cognitive problems related to Alzheimer’s disease and related dementias regain memory and thinking skills after discharge.

  NIH research Vanderbilt University · Nashville, UNITED STATES · NIH-11332902

• Early warning monitors for very small premature babies in the NICU

  Uses advanced computer analysis of bedside monitor data to find early signs of infection and serious gut disease in very low birth weight premature infants.

  NIH research University of Virginia · Charlottesville, United States · NIH-11327642

• Improving mobile photon-counting CT scans for brain patients in the neuro ICU

  Aiming to make bedside brain CT images from a mobile scanner clearer using deep learning, so doctors can diagnose faster without moving the patient.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11326200

• Improving access to top-level newborn intensive care for very-small babies

  This project looks at how state and hospital transfer rules for high-risk moms and babies affect where very-low-birth-weight infants are born and their health, especially for racial and ethnic groups with worse outcomes.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11321146

• Engaging family caregivers in ICU care with FamilyRoom.Health

  A program tests a patient-facing digital platform that helps family caregivers participate more effectively in ICU care.

  NIH research Family Room LLC · Lincoln, United States · NIH-11313259

• Tailoring blood pressure to protect brain blood flow during and after heart surgery

  Aims to see if monitoring each person's brain blood-flow limits and personalizing blood-pressure targets during and after heart surgery reduces delirium and longer-term memory and thinking problems.

  NIH research Stanford University · Stanford, United States · NIH-11310140

• Virtual family-centered rounds to improve care and family well-being in the PICU

  A family-focused telehealth approach is tested to help caregivers participate in rounds and improve care and psychosocial outcomes for kids in the PICU.

  NIH research University of California at Davis · Davis, United States · NIH-11296759

• Understanding how sepsis affects recovery in children after intensive care

  This study is looking at how sepsis affects kids' physical abilities over time after they've been treated in the PICU, to help us understand their recovery better and improve care for future patients.

  NIH research University of Connecticut Storrs · Storrs-Mansfield, United States · NIH-11195327

• Balancing work and family after a NICU stay

  This project follows parents of very preterm infants to understand how they manage returning to work and caring for their baby, with special attention to Black and low-income families.

  NIH research Women and Infants Hospital-Rhode Island · Providence, United States · NIH-11194267

• Understanding sleep, pain, and recovery in children after intensive care

  This project aims to understand how sleep and pain affect the long-term recovery of children who have been in a pediatric intensive care unit.

  NIH research Oregon Health & Science University · Portland, United States · NIH-11194241

• How NICU light and noise affect early brain and hearing development

  This work looks at whether bright lights and loud sounds like those in the NICU can change early brain and hearing development relevant to infants born prematurely.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11190849

• Helping preterm babies in the NICU grow and develop better with gentle sensory experiences

  This project aims to help very preterm babies in the NICU develop well by providing them with gentle, positive sensory experiences and supporting their parents.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11169838

• Screening and support for families' social needs in the NICU

  This project brings routine screening for housing, food, and other social needs to parents of preterm babies in the neonatal intensive care unit and connects families to community services.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11168947

• Internet CBT to reduce depression and memory decline after an ICU stay

  This project offers online cognitive behavioral therapy to help reduce depression and slow thinking and memory problems in older adults who survived an intensive care unit stay.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11166462

• Improving recovery for ICU survivors with cognitive impairments through telehealth

  This study is looking at how using telehealth can help patients who have been in the ICU recover better, especially those dealing with memory and thinking problems after serious illnesses like sepsis or acute respiratory distress syndrome, by making it easier for them to get care from home.

  NIH research Vanderbilt University · Nashville, UNITED STATES · NIH-11142674

• Improving image quality of mobile CT scans for brain care in intensive care units

  This study is working on making the pictures from mobile CT scanners used in neuro intensive care units clearer and more accurate, so doctors can better diagnose serious conditions like strokes and bleeding in patients without having to move them around.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11121759

• Improving language exposure for infants in neonatal intensive care units

  This study is all about helping babies in the NICU by encouraging parents and doctors to talk to them more in a special way that supports their language development, making it easier for these little ones to grow and learn.

  NIH research Henry Ford Health System · Detroit, United States · NIH-11109442

• Understanding how NICU room changes affect babies and families

  This project looks at how changing NICU rooms from open spaces to private family rooms affects the health of babies and the experiences of their families, especially focusing on differences among various racial and income groups.

  NIH research North Carolina Agri & Tech St Univ · Greensboro, United States · NIH-11099964

• Understanding barriers to family engagement in neonatal intensive care units

  This study is looking at the difficulties that low-income families face when trying to connect with their premature babies in the NICU, like issues with transportation and language, to find ways to help them be more involved and improve their babies' health.

  NIH research Stanford University · Stanford, United States · NIH-11093465

• Improving family communication in the ICU and its effect on health

  This project looks at how well healthcare teams talk with family members in the intensive care unit and how that communication affects family well-being and patient care.

  NIH research Pennsylvania State Univ Hershey Med Ctr · Hershey, United States · NIH-11090453

• Helping patients with acute brain injuries and their caregivers build resilience together

  This study is for patients who have had a brain injury, like a stroke, and their caregivers, and it offers a friendly program called 'Recovering Together' to help them cope with stress and support each other while they heal in the hospital.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11090444

• Understanding how sleep affects delirium in ICU patients

  This study is looking at how sleep patterns might affect older adults who are in the ICU after thoracic surgery, to see if poor sleep could lead to confusion or delirium during their hospital stay, with the goal of finding ways to help them feel better.

  NIH research Vanderbilt University · Nashville, UNITED STATES · NIH-11087537

• Improving how intensive care units are staffed in the U.S.

  This study is looking at how to make intensive care units (ICUs) better for patients with serious breathing problems by figuring out the best ways to organize staff and teams, so that doctors can provide the best care possible.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11063832

• Helping parents of babies in the NICU build resilience

  This study is testing a new program called Resilient Families (R-FAM) to help parents of newborns in the NICU manage the emotional stress of having a baby in the hospital, and it’s designed with input from parents and staff to make sure it meets their needs.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11058360

• Improving access to high-level neonatal care for infants

  This study looks at how different groups of families, especially those from minority backgrounds, can have trouble getting their tiny babies the best care in special hospitals, and it aims to find ways to improve access and health outcomes for these vulnerable infants.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11020527

• A virtual reality application to reduce delirium in ICU patients.

  This study is testing a virtual reality program that helps ICU patients stay mentally active, sleep better, and move around more, all to prevent confusion and improve their recovery, while making it easier for nurses to provide care.

  NIH research Ralphvr INC. · Lexington, United States · NIH-11007082

• Using online therapy to help older ICU survivors with depression and cognitive decline

  This study is looking at whether online therapy can help older adults who have been in intensive care feel better mentally and improve their thinking skills, especially focusing on those from different backgrounds.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-10999495

• Improving how intensive care units use evidence-based treatments for patients with respiratory failure

  This study looks at how ICU teams work together and make decisions to help ensure that patients with serious breathing problems get the best treatments based on the latest medical research.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10987021

Related topics

Quick answers

How many Intensive Care clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in France (4 trials), Austria (2 trials), China (2 trials), Taiwan (1 trial), Turkey (Türkiye) (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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