NIH-funded research R01 grant

Helping preterm babies in the NICU grow and develop better with gentle sensory experiences

Official title: Multisensory interventions to improve neurodevelopmental outcomes of preterm infants hospitalized in the neonatal intensive care unit

Funded at University of Southern California · NIH-11169838 · Data updated 2026-11-12

This project aims to help very preterm babies in the NICU develop well by providing them with gentle, positive sensory experiences and supporting their parents.

More Intensive Care Unit research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Southern California
NIH-funded
Lab location1 site (Los Angeles, UNITED STATES)
Project startJuly 1, 2022
Project endAugust 31, 2027
Funding year2025
Award (this year)$672,443
NIH project number5R01HD105557-04
Project IDNIH-11169838 on NIH RePORTER

Who could benefit from this research

Could help

This project is designed for very preterm infants who are hospitalized in the neonatal intensive care unit (NICU).

Less likely to help

Patients who are not preterm infants or are not receiving care in a neonatal intensive care unit would not directly benefit from this specific program.

What this research studies

When babies are born very early, they often spend their first months in the NICU, where they might miss out on important positive sensory experiences and time with their parents, which can affect their brain development. Our program, called SENSE, offers a structured way to give these babies specific gentle sensory activities like massage, soft sounds, rocking, holding, and skin-to-skin care. These activities are carefully timed and chosen based on each baby's developmental stage. We also help parents learn how to engage with their baby in the NICU to strengthen their bond and support their baby's growth.

Why it matters

Potential benefit: If successful, this program could lead to better brain development and overall well-being for preterm infants, and help parents feel more connected and involved in their baby's care.

How similar studies have gone: While other studies support positive multisensory interventions, this project introduces a new, structured program called SENSE to apply these interventions consistently.

Where this research is happening

  • University of Southern California
    Los Angeles, United States
    Active

Researchers

  • Principal investigator: Pineda, Roberta — University of Southern California
  • Study coordinator: Pineda, Roberta

Related research

Other NIH-funded projects on the same topics.

  • Multisensory care to boost development in preterm babies in the NICU

    A program called SENSE uses gentle touch, sounds, and parent bonding in the NICU to support brain development for very preterm infants and help families stay involved.

    NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11378465

  • Improving care for preterm infants in the neonatal intensive care unit

    This study is testing a special program called SENSE to help preterm babies in the NICU grow and develop better by using gentle touch, sounds, and skin-to-skin time, while also helping parents connect with their little ones during their hospital stay.

    NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-10892638

  • Phthalate Exposure and How It Affects Newborns in the NICU

    This grant looks at how chemicals called phthalates in the NICU environment may affect the health and development of newborns, especially those born prematurely.

    NIH research Feinstein Institute for Medical Research · Manhasset, United States · NIH-11594454

  • Improving care for opioid use disorder in the ICU

    This project helps hospital staff in intensive care units provide better care for patients with opioid use disorder.

    NIH research Mainehealth · Portland, United States · NIH-11477142

  • Juggling Work and Family for Parents of Very Preterm Babies

    A study to understand how work and family demands affect parents of very preterm infants and how this shapes their ability to support their baby’s development.

    NIH research Women and Infants Hospital-Rhode Island · Providence, United States · NIH-11413664

  • Implementing SDOH screening and referrals in the NICU to support fragile newborns

    A NICU-based program to screen newborns and families for social needs and connect them to services that can improve health and development.

    NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11398100

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.