Monitoring blood flow and response to fluids in patients on ECMO
Validation of Techniques for Hemodynamic Monitoring and Prediction of Fluid Responsiveness in Patients Undergoing Venoarterial Extracorporeal Membrane Oxygenation - A Prospective Diagnostic Accuracy Study ("HemodynamECMOnitoring-VA Study")
This study is testing different ways to monitor blood flow and heart function in adults receiving VA ECMO treatment to see which methods work best for their care.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Medical University of Vienna Academic / other |
| Locations | 1 site (Vienna) |
| Trial ID | NCT06593756 on ClinicalTrials.gov |
What this trial studies
This study focuses on evaluating the accuracy of various hemodynamic monitoring techniques during venoarterial extracorporeal membrane oxygenation (VA ECMO) treatment. It aims to assess methods such as transthoracic echocardiography, pulse contour analysis, and transpulmonary thermodilution to ensure accurate monitoring of cardiac function and circulatory status. The study will involve patients receiving VA ECMO support, aged 18 to 75, and will exclude those with certain medical conditions that prevent specific maneuvers. By validating these techniques, the study seeks to improve patient management in intensive care settings.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 to 75 who are receiving VA ECMO support.
Not a fit: Patients who are pregnant or have conditions that prevent passive leg raising maneuvers will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy of hemodynamic monitoring in ECMO patients, leading to better clinical outcomes.
How similar studies have performed: While hemodynamic monitoring techniques have been validated in various clinical scenarios, this specific application in VA ECMO is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient receiving VA ECMO support * Age 18 - 75 years Exclusion Criteria: * Pregnancy * Conditions not allowing for passive leg raising maneuvers, e.g. "open abdomen", known or suspected elevation of intracranial pressure, recent leg or spinal trauma or orthopedic conditions not permitting leg raising * Known ischemic or hemorrhagic stroke within 3 months prior to study enrollment.
Where this trial is running
Vienna
- Medical University of Vienna — Vienna, Austria (Recruiting)
Study contacts
- Study coordinator: Bernhard Nagler, MD
- Email: bernhard.nagler@meduniwien.ac.at
- Phone: +4314040044920
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.