Monitoring blood flow and response to fluids in patients on ECMO
Official title: Validation of Techniques for Hemodynamic Monitoring and Prediction of Fluid Responsiveness in Patients Undergoing Venoarterial Extracorporeal Membrane Oxygenation - A Prospective Diagnostic Accuracy Study ("HemodynamECMOnitoring-VA Study")
Run by Medical University of Vienna · NCT06593756 · Data updated 2026-11-12
This study is testing different ways to monitor blood flow and heart function in adults receiving VA ECMO treatment to see which methods work best for their care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Medical University of Vienna Academic / other |
| Locations | 1 site (Vienna) |
| Status | Recruiting |
| Started | May 3, 2024 |
| Main results expected | January 2027 |
| Study ends | January 2027 |
| Registry record updated | September 29, 2025 |
| Trial ID | NCT06593756 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 to 75 who are receiving VA ECMO support.
✕Probably not a fit
Patients who are pregnant or have conditions that prevent passive leg raising maneuvers will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on evaluating the accuracy of various hemodynamic monitoring techniques during venoarterial extracorporeal membrane oxygenation (VA ECMO) treatment. It aims to assess methods such as transthoracic echocardiography, pulse contour analysis, and transpulmonary thermodilution to ensure accurate monitoring of cardiac function and circulatory status. The study will involve patients receiving VA ECMO support, aged 18 to 75, and will exclude those with certain medical conditions that prevent specific maneuvers. By validating these techniques, the study seeks to improve patient management in intensive care settings.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy of hemodynamic monitoring in ECMO patients, leading to better clinical outcomes.
How similar studies have gone: While hemodynamic monitoring techniques have been validated in various clinical scenarios, this specific application in VA ECMO is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient receiving VA ECMO support * Age 18 - 75 years Exclusion Criteria: * Pregnancy * Conditions not allowing for passive leg raising maneuvers, e.g. "open abdomen", known or suspected elevation of intracranial pressure, recent leg or spinal trauma or orthopedic conditions not permitting leg raising * Known ischemic or hemorrhagic stroke within 3 months prior to study enrollment.
Where it's running
-
Medical University of Vienna
Vienna, Austria Recruiting
Study contacts
- Study coordinator: Bernhard Nagler, MD
- Email: bernhard.nagler@meduniwien.ac.at
- Phone: +4314040044920
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.