Improving mobile photon-counting CT scans for brain patients in the neuro ICU
Official title: Optimizing Mobile Photon-Counting CT Image Quality via Deep Learning for Neuro Intensive Care Unit
Funded at Ohio State University · NIH-11326200 · Data updated 2026-11-12
Aiming to make bedside brain CT images from a mobile scanner clearer using deep learning, so doctors can diagnose faster without moving the patient.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | July 1, 2024 |
| Project end | April 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $359,314 |
| NIH project number | 5R01EB035394-04 |
| Project ID | NIH-11326200 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients in the neuro intensive care unit who require bedside brain CT imaging.
✕Less likely to help
Patients whose scans are not limited by noise or artifacts may see little direct benefit.
What this research studies
This project uses an FDA-approved mobile photon-counting CT and advanced image reconstruction with deep learning to reduce noise and artifacts in brain scans done in the neuro ICU. By creating low-dose, high-resolution reconstruction methods and exploring material decomposition, it seeks to make mobile CT images comparable to fixed scanners. The work focuses on improving gray-white matter contrast and detecting small strokes or bleeds without transporting critically ill patients. If successful, this could lead to quicker, safer decisions at the bedside.
Why it matters
Potential benefit: Potentially clearer bedside brain scans could improve diagnosis and treatment while avoiding risks of moving critically ill patients.
How similar studies have gone: Prior deep learning approaches have shown improvements in CT image quality, with this work pushing toward parity with fixed scanners in a clinical setting.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Wu, Dufan — Ohio State University
- Study coordinator: Wu, Dufan
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Improving image quality of mobile CT scans for brain care in intensive care units
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.