NIH-funded research R21 grant

How NICU light and noise affect early brain and hearing development

Official title: An Animal Model of Neonatal Intensive Care Unit Exposure to Light and Sound

Funded at Rutgers Biomedical and Health Sciences · NIH-11190849 · Data updated 2026-11-12

This work looks at whether bright lights and loud sounds like those in the NICU can change early brain and hearing development relevant to infants born prematurely.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionRutgers Biomedical and Health Sciences
NIH-funded
Lab location1 site (Newark, UNITED STATES)
Project startSeptember 10, 2024
Project endAugust 31, 2026
Funding year2025
Award (this year)$196,250
NIH project number5R21HD114995-02
Project IDNIH-11190849 on NIH RePORTER

Who could benefit from this research

Could help

This work is most relevant to infants born prematurely who spend time in the NICU and are at risk for hearing, vision, or cognitive delays.

Less likely to help

Full-term infants without NICU exposure or people whose hearing or vision problems come from genetic or non-environmental causes are unlikely to benefit directly from this specific project.

What this research studies

If your baby was born early, this research explores whether the light and noise they experience in the NICU can change how their brain and hearing develop. To do that, scientists use a Mongolian gerbil model whose hearing is similar to humans and open the animals' eyes and ears early to mimic preterm birth. The animals are then exposed to NICU-like levels of light and sound during the brain's early critical period, and researchers record brain and ear responses to track lasting changes. The project combines anatomy, electrophysiology, and behavioral measures to understand how early visual input might alter auditory development.

Why it matters

Potential benefit: If successful, the findings could point to environmental changes or protective strategies in NICUs that reduce lifelong hearing, vision, or learning problems after preterm birth.

How similar studies have gone: Previous animal studies, including recent preliminary work, suggest early light and sound can affect long-term brain development, but translation to human care practices is not yet established.

Where this research is happening

  • Rutgers Biomedical and Health Sciences
    Newark, United States
    Active

Researchers

  • Principal investigator: Mowery, Todd M. — Rutgers Biomedical and Health Sciences
  • Study coordinator: Mowery, Todd M.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.