Predicting rehabilitation outcomes for ICU patients on mechanical ventilation
Development and Validation of a Prediction Algorithms to Estimate the Clinical Effect of Early Rehabilitation on ICU Survivors Received Mechanical Ventilation in the ICU
Wuhan University · NCT06532994
This study is trying to see if early rehabilitation can help ICU patients on mechanical ventilation recover better and which patients are most likely to benefit from it.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Wuhan University (other) |
| Locations | 1 site (Wuhan, Hubei) |
| Trial ID | NCT06532994 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of early rehabilitation interventions for patients who have received mechanical ventilation in the ICU. It aims to collect clinical data from these patients to develop a predictive model that identifies which individuals are likely to benefit from rehabilitation. By utilizing guidelines for reporting multivariable prediction models, the study will analyze various predictors, including demographic and clinical data, to assess improvements in daily living activities post-rehabilitation. The ultimate goal is to enhance recovery strategies for ICU survivors.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 who have received mechanical ventilation during their ICU stay and have undergone early rehabilitation interventions.
Not a fit: Patients who did not receive mechanical ventilation or those who experienced mortality events during ICU admission may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more personalized rehabilitation strategies, improving recovery outcomes for ICU patients.
How similar studies have performed: Other studies have shown promising results with early rehabilitation interventions in ICU settings, suggesting that this approach is both feasible and beneficial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age older than 18 years; 2. Received mechanical ventilation, including endotracheal intubation and tracheostomy, during ICU admission; 3. Met the rehabilitation intervention indications outlined in the "Chinese Expert Consensus on Neurocritical Rehabilitation" during ICU admission and underwent corresponding early rehabilitation interventions, including but not limited to arousal therapy for consciousness disorders, early active/passive mobilization, comprehensive pulmonary rehabilitation, etc.; 4. No mortality events occurred during ICU admission; 5. Informed consent form signed by family members or the patient. Exclusion Criteria: 1. Pediatric patients under 18 years of age; 2. Hospitalized patients in the ICU who did not receive mechanical ventilation; 3. Patients in the ICU who did not undergo early rehabilitation interventions; 4. mortality events occurred during ICU admission; 5. Patients transferred out of the ICU due to treatment abandonment by family members; 6. Family refusal to sign the informed consent form or patient refusal to sign the informed consent form when conscious and competent.
Where this trial is running
Wuhan, Hubei
- Zhongnan hospital of Wuhan University — Wuhan, Hubei, China (RECRUITING)
Study contacts
- Study coordinator: Qing' Shu, Ph.D
- Email: shuqingj@whu.edu.cn
- Phone: +86 13971081682
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Intensive Care, Mechanical Ventilation, Rehabilitation, Algorithms