Improving lung function during chest physiotherapy for patients on mechanical ventilation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of respiratory physiotherapy techniques, specifically Rib Cage Compressions (RCC), in mechanically ventilated patients. It aims to compare the pulmonary recruitment achieved during physiotherapy sessions conducted under two different ventilatory modes: Volume Assist Control Ventilation (V-ACV) and Pressure Support Ventilation (PSV). The primary outcome is the change in end-expiratory lung volume (ΔEELV) measured before and after the physiotherapy sessions. Secondary outcomes include assessments of respiratory mechanics, gas exchange, and patient tolerance. The study employs advanced measurement tools to evaluate the impact of these techniques on lung function.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient under assisted ventilation (in V-ACV or PSV) triggering all ventilator cycles
* Patient deemed " secretive ": requiring ≥ 2 tracheal aspirations every 3 hours
* Patient (or relative) who has given consent to participate in the research
* Patient covered by social security

Exclusion Criteria:

* Age under 18 years
* Legal guardian required
* Recent cardiac and/or thoracic and/or abdominal surgery (\< 3 months)
* Rib fracture(s)
* Pneumothorax and/or presence of a chest drain
* Recent neurosurgery (\< 3 months) and/or proven or suspected increased intracranial pressure (ICP)
* Hemodynamic instability defined as: noradrenaline ≥ 1mg/h, adrenaline ≥ 0.5 mg/h, dobutamine ≥ 5γ/kg/min.
* Respiratory instability defined as: PEEP \> 10 cmH2O and/or PaO2/FiO2 \< 150 mm Hg
* Pregnancy
* Hemoptysis
* Sever skin lesions (e.g., burns, Lyell's syndrome)
* Patient under foreign health insurance

Where it's running

• Intensive Care Medicine Department Henri Mondor Hospital
  Créteil, France Recruiting

Study contacts

• Study coordinator: Guillaume Pr CARTEAUX, MD,PhD
• Email: guillaume.carteaux@aphp.fr
• Phone: 01 45 17 86 38

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.