Condition

Carpal Tunnel Syndrome clinical trials and research

• 25Clinical trials
• 4NIH research projects
• 11Countries

Newest Carpal Tunnel Syndrome clinical trials

All recruiting trials (25)

• Matrix Rhythm Therapy for Carpal Tunnel Syndrome

  This study tests whether adding Matrix Rhythm Therapy to standard care helps people with mild-to-moderate carpal tunnel syndrome improve symptoms, hand function, grip and pinch strength, and quality of life.

  Recruiting Izmir Bakircay University · Izmir · NCT07660913

• Carpal tunnel release vs placebo surgery in Finland

  In this trial, people with carpal tunnel syndrome are randomly assigned to either standard carpal tunnel surgery or a pretend surgery to see if relief comes from the operation itself or from placebo effects.

  Recruiting at 2 sites Helsinki University Central Hospital · Helsinki and 1 other locations · NCT07614425

• High-intensity laser therapy for carpal tunnel syndrome

  This trial will test whether high-intensity laser therapy helps adults 18–65 with mild-to-moderate carpal tunnel syndrome reduce pain and improve nerve function and hand strength compared with a sham procedure.

  Recruiting Ankara City Hospital Bilkent · Ankara, Ankara, Çankaya · NCT07414069

• Ultrasound-guided needle release plus dextrose (D5W) hydrodissection for carpal tunnel syndrome

  This trial tests whether combining ultrasound-guided partial release of the transverse carpal ligament with dextrose (D5W) hydrodissection provides better symptom relief for adults with carpal tunnel syndrome and at least moderate symptoms.

  Recruiting Shin Kong Wu Ho-Su Memorial Hospital · Taipei · NCT07324005

• A mix of vitamins to help recovery after carpal tunnel surgery

  This will test whether taking alpha-lipoic acid, vitamin E, and B vitamins helps adults recover better after carpal tunnel release surgery.

  Recruiting Hospital Universiti Sains Malaysia · Kubang Kerian, Kelantan · NCT07312123

• Symptom spread and pain sensitivity in carpal tunnel syndrome

  This test looks at whether people with carpal tunnel syndrome whose symptoms spread beyond the usual finger area have higher central pain sensitivity, using a questionnaire and pressure pain testing.

  Recruiting Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey · Istanbul, Usküdar · NCT07114913

• Using ultrasound to improve diagnosis and management of carpal tunnel syndrome

  This study is testing if using ultrasound can help doctors diagnose and manage carpal tunnel syndrome better than the usual nerve tests.

  Recruiting Kafrelsheikh University · Kafr ash Shaykh, Kafrelsheikh · NCT06834061

• Using kinesiology tape to treat carpal tunnel symptoms in esports gamers

  This study tests if kinesiology tape can help esports gamers with carpal tunnel symptoms while still allowing them to perform well in their games.

  Recruiting University of Nevada, Las Vegas · Las Vegas, Nevada · NCT06757062

• Comparing ultrasound-guided corticosteroid injections and paraffin therapy for carpal tunnel syndrome

  This study is testing whether ultrasound-guided corticosteroid injections or paraffin therapy works better to relieve pain and improve function in people with mild to moderate carpal tunnel syndrome.

  Recruiting Beylikduzu State Hospital · Istanbul, Beylikdüzü · NCT06658886

• Desensitisation with or without pain neuroscience education for mixed neuropathic/nosiplastic carpal tunnel pain

  This trial will test whether adding pain neuroscience education to desensitisation helps adults (18–65) with carpal tunnel syndrome who have a mixed neuropathic and nosiplastic pain pattern.

  Recruiting Kutahya Health Sciences University · Kütahya · NCT06635213

• Assessing small nerve fiber activity in carpal tunnel syndrome patients through sensory testing

  This study is testing how physical therapy affects small nerve fibers in people with carpal tunnel syndrome to see if it improves their symptoms and nerve function.

  Recruiting Brooke Army Medical Center · San Antonio, Texas · NCT06550284

• Examining median nerve variations in carpal tunnel syndrome patients

  This study is trying to see if certain variations in the median nerve are more common in people with carpal tunnel syndrome compared to those who don’t have it.

  Recruiting Ankara Etlik City Hospital · Ankara, Ankara · NCT06538779

• Diagnosing ATTR Cardiac Amyloidosis in Patients with Carpal Tunnel Syndrome

  This study is testing if patients with carpal tunnel syndrome might also have a heart condition called ATTR amyloidosis by doing tests and following them for 10 years.

  Recruiting Helse Møre og Romsdal HF · Ålesund, Møre og Romsdal · NCT06458374

• Ultrasound-guided carpal tunnel release procedure

  This study is testing a new ultrasound-guided method for treating carpal tunnel syndrome to see if it can help patients recover faster and with less pain than traditional surgery.

  Recruiting Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT06440070

• Comparing ultrasound-guided injections to surgery for carpal tunnel syndrome

  This study is testing whether ultrasound-guided injections or small surgery works better to relieve symptoms for people with carpal tunnel syndrome.

  Recruiting Afyonkarahisar Health Sciences University · Afyonkarahisar · NCT06243848

• Assessing a Thai version of a questionnaire for diagnosing Carpal Tunnel Syndrome

  This study is testing a Thai version of a questionnaire to see if it can help doctors better diagnose Carpal Tunnel Syndrome in patients who have symptoms of the condition.

  Recruiting Siriraj Hospital · Bangkok Noi, Bangkok · NCT06239259

• Device for treating carpal tunnel syndrome

  This study tests a new device that gently pushes on the wrist while you sleep to see if it helps people with carpal tunnel syndrome feel better compared to using a regular wrist brace.

  Recruiting University of Arizona · Tucson, Arizona · NCT06208709

• Cooling therapy for pain relief after carpal tunnel surgery

  This study is testing if a new cooling therapy can help people feel less pain after carpal tunnel surgery compared to regular ice packs.

  Recruiting University of Chicago · Chicago, Illinois · NCT05783245

• Examining how carpal tunnel syndrome affects sleep quality

  This study looks at how carpal tunnel syndrome affects sleep quality in patients compared to healthy people to see if there's a connection between the two.

  Recruiting Afyonkarahisar Health Sciences University · Afyonkarahisar, Afyonkarahi̇sar · NCT05742776

• Comparing night-time and full-time splinting for carpal tunnel syndrome

  This study is testing whether wearing a splint at night or all day helps people with carpal tunnel syndrome feel better and if it can reduce the need for surgery.

  Recruiting at 5 sites Tampere University Hospital · Helsinki and 5 other locations · NCT05637294

• Comparing absorbable and non-absorbable sutures for carpal tunnel surgery

  This study is testing whether using absorbable or non-absorbable stitches during carpal tunnel surgery affects the chances of getting an infection afterward.

  Recruiting at 2 sites Gelre Hospitals · Apeldoorn and 1 other locations · NCT05431101

• Carpal tunnel release surgery with different anesthesia methods

  This study tests if adding a nerve block to local anesthesia during carpal tunnel release surgery can help reduce pain for patients compared to just using local anesthesia.

  Recruiting Kuopio University Hospital · Kuopio, Northern Savonia · NCT05372393

• Evaluating nerve damage risk after radial artery procedures

  This study is testing if patients who have procedures on their radial artery for heart disease experience nerve damage by checking their nerve function before and after the procedure.

  Recruiting Aarhus University Hospital Skejby · Aarhus · NCT05365282

• Noninvasive brain stimulation for carpal tunnel syndrome treatment

  This study is testing if a new noninvasive brain stimulation treatment can help reduce pain for people with Carpal Tunnel Syndrome.

  Recruiting Spaulding Rehabilitation Hospital · Charlestown, Massachusetts · NCT04206215

• Using Exparel and education to reduce opioid use after carpal tunnel surgery

  This study is testing if using Exparel along with education on opioid use can help people have less pain and use fewer opioids after carpal tunnel surgery.

  Recruiting at 2 sites Phase 4 Kettering Health Network · Dayton, Ohio and 1 other locations · NCT03867539

NIH-funded research (4)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• How aged cells contribute to carpal tunnel syndrome

  This project tests whether clearing out aged 'senescent' cells in the wrist's connective tissue can reduce scarring and nerve pressure for people with carpal tunnel syndrome.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11238565

• New treatment for carpal tunnel syndrome in Hispanic women

  This study is looking at a new non-surgical treatment called carpal arch space augmentation (CASA) to see if it can help Hispanic women with carpal tunnel syndrome feel better and use their hands more easily, comparing it to the usual brace treatment over eight weeks.

  NIH research University of Arizona · Tucson, United States · NIH-11014617

• Understanding how aging cells contribute to Carpal Tunnel Syndrome

  This study is looking at how aging cells might play a part in causing Carpal Tunnel Syndrome, which affects many people, and it aims to find ways to treat this condition by focusing on those aging cells to help improve symptoms for patients.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-10996173

• Using brain stimulation to improve physical therapy for carpal tunnel syndrome

  This study is exploring a new way to help people with carpal tunnel syndrome by using a special non-invasive treatment that targets how the brain processes pain, aiming to make physical therapy more effective and reduce chronic pain.

  NIH research Highland Instruments, INC. · Cambridge, United States · NIH-10706948

Related topics

Quick answers

How many Carpal Tunnel Syndrome clinical trials are recruiting right now?

25, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in Turkey (Türkiye) (8 trials), United States (6 trials), Finland (3 trials), Taiwan (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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