Carpal tunnel release surgery with different anesthesia methods

Carpal Tunnel Release Under Local Anaesthesia With or Without Distal Median Nerve Block - a Protocol of a Double Blinded Randomised Controlled Trial

NA · Kuopio University Hospital · NCT05372393

This study tests if adding a nerve block to local anesthesia during carpal tunnel release surgery can help reduce pain for patients compared to just using local anesthesia.

Quick facts

PhaseNA
Study typeInterventional
Enrollment118 (estimated)
Ages18 Years and up
SexAll
SponsorKuopio University Hospital (other)
Locations1 site (Kuopio, Northern Savonia)
Trial IDNCT05372393 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness of adding a distal median nerve block to local anesthesia during carpal tunnel release surgery. The study aims to determine if this combination reduces pain experienced by patients during and after the procedure compared to using local anesthesia alone. Participants with confirmed carpal tunnel syndrome will be randomly assigned to one of two groups for the surgery. The trial seeks to provide evidence on the best anesthesia approach for this common surgical procedure.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 17 years old with confirmed carpal tunnel syndrome.

Not a fit: Patients with recurrent carpal tunnel syndrome or those with peripheral neuropathies may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management for patients undergoing carpal tunnel release surgery.

How similar studies have performed: While there have been studies on anesthesia methods for carpal tunnel release, this specific comparison of local anesthesia with and without a distal median nerve block is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ≥18 years of age
* CTS verified by nerve conduction studies
* Symptoms suitable for CTS

Exclusion Criteria:

* Recurrent CTS
* Peripheral neuropathies
* Known allergy to the trial drugs
* Profound cognitive impairment
* Pregnancy

Where this trial is running

Kuopio, Northern Savonia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Carpal Tunnel Syndrome, carpal tunnel syndrome, carpal tunnel release, local anaesthesia, surgery, wide-awake local anaesthesia with no tourniquet, nerve block

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.