Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Carpal tunnel release surgery with different anesthesia methods

Official title: Carpal Tunnel Release Under Local Anaesthesia With or Without Distal Median Nerve Block - a Protocol of a Double Blinded Randomised Controlled Trial

Run by Kuopio University Hospital · NCT05372393 · Data updated 2026-11-12

This study tests if adding a nerve block to local anesthesia during carpal tunnel release surgery can help reduce pain for patients compared to just using local anesthesia.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment118 (estimated)
SponsorKuopio University Hospital
Academic / other
Locations1 site (Kuopio, Northern Savonia)
StatusRecruiting
StartedSeptember 21, 2022
Main results expectedDecember 2025
Study endsApril 2026
Registry record updatedSeptember 19, 2025
Trial IDNCT05372393 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults over 17 years old with confirmed carpal tunnel syndrome.

Probably not a fit

Patients with recurrent carpal tunnel syndrome or those with peripheral neuropathies may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of adding a distal median nerve block to local anesthesia during carpal tunnel release surgery. The study aims to determine if this combination reduces pain experienced by patients during and after the procedure compared to using local anesthesia alone. Participants with confirmed carpal tunnel syndrome will be randomly assigned to one of two groups for the surgery. The trial seeks to provide evidence on the best anesthesia approach for this common surgical procedure.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management for patients undergoing carpal tunnel release surgery.

How similar studies have gone: While there have been studies on anesthesia methods for carpal tunnel release, this specific comparison of local anesthesia with and without a distal median nerve block is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ≥18 years of age
* CTS verified by nerve conduction studies
* Symptoms suitable for CTS

Exclusion Criteria:

* Recurrent CTS
* Peripheral neuropathies
* Known allergy to the trial drugs
* Profound cognitive impairment
* Pregnancy

Where it's running

  • Kuopio University hospital, Department of Orthopaedics, Traumatology and Hand Surgery
    Kuopio, Northern Savonia, Finland
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.