Clinical trial Recruiting at 1 site Observational Ages 18 to 65

Examining median nerve variations in carpal tunnel syndrome patients

Official title: Sonographic Examination of Median Nerve Variations and Characteristics Observed in Healthy and Carpal Tunnel Syndrome Patients

Run by Ankara Etlik City Hospital · NCT06538779 · Data updated 2026-11-12

This study is trying to see if certain variations in the median nerve are more common in people with carpal tunnel syndrome compared to those who don’t have it.

More Carpal Tunnel Syndrome trials

Quick facts

Study typeObservational
Ages18 Years to 65 Years
SexAll
Enrollment129 (estimated)
SponsorAnkara Etlik City Hospital
Government
Locations1 site (Ankara, Ankara)
StatusRecruiting
StartedSeptember 1, 2024
Main results expectedSeptember 1, 2025
Study endsSeptember 1, 2025
Registry record updatedMay 30, 2025
Trial IDNCT06538779 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals over 18 years old who have typical symptoms of carpal tunnel syndrome lasting longer than three months and have been diagnosed with CTS via electromyography.

Probably not a fit

Patients with a history of polyneuropathy, brachial plexopathy, or other specified conditions, as well as those who have undergone wrist surgery, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the prevalence of bifid median nerve variations in patients diagnosed with carpal tunnel syndrome (CTS) compared to asymptomatic individuals. It will include patients who have been electrophysiologically diagnosed with CTS at Etlik City Hospital's physical therapy outpatient clinic. Over the course of one year, the study will assess demographic and clinical characteristics, pain levels, symptom severity, and functional status using various measurement tools, including ultrasound and electromyography. The goal is to determine if median nerve variations are predisposing factors for CTS.

Why it matters

Potential benefit: If successful, this study could enhance understanding of the anatomical variations associated with carpal tunnel syndrome, potentially leading to improved diagnostic and treatment strategies.

How similar studies have gone: While the specific examination of bifid median nerve variations in CTS patients may be novel, similar studies have explored median nerve anatomy and its implications in carpal tunnel syndrome.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Having typical Carpal Tunnel Sydnrome symptoms lasting longer than 3 months
* Carpal tunnel syndrome diagnosed with EMG
* Being a male/female \>18 years of age

Exclusion Criteria:

* History of polyneuropathy, brachial plexopathy, thoracic outlet syndrome, or surgery in the wrist area
* Presence of inflammatory arthritis, hypothyroidism, pregnancy, rheumatological disorders, diabetes mellitus
* Presence of peripheral vascular disease

Where it's running

  • Etlik City Hospital
    Ankara, Ankara, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Matrix Rhythm Therapy for Carpal Tunnel Syndrome

    This study tests whether adding Matrix Rhythm Therapy to standard care helps people with mild-to-moderate carpal tunnel syndrome improve symptoms, hand function, grip and pinch strength, and quality of life.

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  • Carpal tunnel release vs placebo surgery in Finland

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  • High-intensity laser therapy for carpal tunnel syndrome

    This trial will test whether high-intensity laser therapy helps adults 18–65 with mild-to-moderate carpal tunnel syndrome reduce pain and improve nerve function and hand strength compared with a sham procedure.

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  • Ultrasound-guided needle release plus dextrose (D5W) hydrodissection for carpal tunnel syndrome

    This trial tests whether combining ultrasound-guided partial release of the transverse carpal ligament with dextrose (D5W) hydrodissection provides better symptom relief for adults with carpal tunnel syndrome and at least moderate symptoms.

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  • A mix of vitamins to help recovery after carpal tunnel surgery

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    Recruiting Hospital Universiti Sains Malaysia · Kubang Kerian, Kelantan · NCT07312123

  • Symptom spread and pain sensitivity in carpal tunnel syndrome

    This test looks at whether people with carpal tunnel syndrome whose symptoms spread beyond the usual finger area have higher central pain sensitivity, using a questionnaire and pressure pain testing.

    Recruiting Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey · Istanbul, Usküdar · NCT07114913

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.