Comparing absorbable and non-absorbable sutures for carpal tunnel surgery
Official title: Absorbable Versus Non-absorbable Sutures for Wound Closure in Carpal Tunnel Release: a Randomized Controlled Trial
Run by Gelre Hospitals · NCT05431101 · Data updated 2026-11-12
This study is testing whether using absorbable or non-absorbable stitches during carpal tunnel surgery affects the chances of getting an infection afterward.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 2604 (estimated) |
| Sponsor | Gelre Hospitals Academic / other |
| Locations | 2 sites (Apeldoorn and 1 other locations) |
| Status | Recruiting |
| Started | May 1, 2022 |
| Main results expected | March 1, 2028 |
| Study ends | April 1, 2028 |
| Registry record updated | August 26, 2025 |
| Trial ID | NCT05431101 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals scheduled for carpal tunnel release surgery.
✕Probably not a fit
Patients who have previously undergone carpal tunnel surgery or have received corticosteroid injections for their condition may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the incidence of wound infections in patients undergoing carpal tunnel release surgery using either absorbable or non-absorbable sutures. Carpal Tunnel Syndrome is a common condition that can lead to significant discomfort and loss of function, and surgical decompression is the most effective treatment. The study aims to determine if the type of suture material used affects the rate of post-surgical infections. The primary outcome will be measured using the ASEPSIS wound score, assessed by independent investigators, while patients will also report their pain levels during recovery.
Why it matters
Potential benefit: If successful, this study could help identify the optimal suture type to reduce the risk of wound infections after carpal tunnel surgery.
How similar studies have gone: While there is ongoing debate in the literature regarding the superiority of absorbable versus non-absorbable sutures, this study aims to provide clearer evidence on the topic.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: • indication for carpal tunnel release Exclusion Criteria: * carpal tunnel syndrome which has yet been operated * injection with corticosteroids
Where it's running
-
Gelre Ziekenhuizen
Apeldoorn, Netherlands Recruiting -
Deventer Ziekenhuis
Deventer, Netherlands Recruiting
Study contacts
- Study coordinator: Pauline Verhaegen, MD PHD
- Email: paulineverhaegen@hotmail.com
- Phone: 0555811244
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Matrix Rhythm Therapy for Carpal Tunnel Syndrome
This study tests whether adding Matrix Rhythm Therapy to standard care helps people with mild-to-moderate carpal tunnel syndrome improve symptoms, hand function, grip and pinch strength, and quality of life.
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Carpal tunnel release vs placebo surgery in Finland
In this trial, people with carpal tunnel syndrome are randomly assigned to either standard carpal tunnel surgery or a pretend surgery to see if relief comes from the operation itself or from placebo effects.
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Cold atmospheric plasma to improve cannulation-site wound healing after extracorporeal life support
This trial will test whether adding cold atmospheric plasma (CAP) to standard wound care helps adults on extracorporeal life support heal cannulation-site wounds faster and with fewer infections.
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High-intensity laser therapy for carpal tunnel syndrome
This trial will test whether high-intensity laser therapy helps adults 18–65 with mild-to-moderate carpal tunnel syndrome reduce pain and improve nerve function and hand strength compared with a sham procedure.
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PowerHeal Bioelectric Bandage for infected open wound recovery
This tests whether the PowerHeal™ Bioelectric Bandage helps adults with infected traumatic wounds heal faster and clear infection better than standard dressings.
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Ultrasound-guided needle release plus dextrose (D5W) hydrodissection for carpal tunnel syndrome
This trial tests whether combining ultrasound-guided partial release of the transverse carpal ligament with dextrose (D5W) hydrodissection provides better symptom relief for adults with carpal tunnel syndrome and at least moderate symptoms.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.