Evaluating nerve damage risk after radial artery procedures

Association Between Radial Artery Intervention and Development of Neuropathy in the Hand - A Prospective Study - The ACCESS IV Study

Observational Aarhus University Hospital Skejby · NCT05365282

This study is testing if patients who have procedures on their radial artery for heart disease experience nerve damage by checking their nerve function before and after the procedure.

Quick facts

Study typeObservational
Enrollment400 (estimated)
Ages18 Years and up
SexAll
SponsorAarhus University Hospital Skejby Academic / other
Locations1 site (Aarhus)
Trial IDNCT05365282 on ClinicalTrials.gov

What this trial studies

This study evaluates the potential for nerve damage in patients undergoing radial artery interventions for ischemic heart disease. Patients scheduled for radial coronary angiography or percutaneous coronary intervention will undergo sensory and motor nerve examinations before and one month after the procedure. Each patient serves as their own control, allowing for a direct comparison of nerve function. Additionally, patients will complete questionnaires regarding hand and arm symptoms and perform specific activities to assess functional impact.

Who should consider this trial

Good fit: Ideal candidates are patients scheduled for radial coronary angiography or PCI who can provide informed consent.

Not a fit: Patients who are pregnant or have a negative Barbeau test will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help identify risks associated with radial artery access, leading to improved patient safety and outcomes.

How similar studies have performed: While this study explores a specific association, similar observational studies have indicated potential risks with radial access, suggesting that this area warrants further investigation.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* The patient must be able to give informed consent

Exclusion Criteria:

* Pregnancy
* Negative Barbeau test

Where this trial is running

Aarhus

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Ischemic Heart DiseaseNerve InjuryCarpal Tunnel SyndromeTransradial accessHand Dysfunction
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.