Condition
Sleep Quality clinical trials and research
As of November 12, 2026, Find a Trial lists 40 Sleep Quality clinical trials that are recruiting, at sites in 20 countries (most in Turkey (Türkiye) (13), United States (10), Belgium (3)). 2 were first registered in the last 30 days. By phase: Phase 3 (1), Phase 2 (1). There are also 7 NIH-funded research projects on Sleep Quality, with $4.5 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 40Clinical trials
- 7NIH research projects
- 2New in 30 days
- 20Countries
Newest Sleep Quality clinical trials
All recruiting trials (40)
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Physical activity habits and sleep/ breathing in obstructive sleep apnea
This study tests whether daily physical activity habits affect sleep quality and breathing measurements in people with obstructive sleep apnea who are on CPAP therapy.
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Shoulder pain patients: see if breathing and chest exercises help pain and sleep
This study tests whether adding respiratory muscle strengthening and diaphragmatic breathing to shoulder rehab can reduce pain and improve sleep in adults with chronic shoulder pain.
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Predictive CGM with App for people with type 1 or insulin-treated type 2 diabetes
This study tests whether using the Accu-Chek SmartGuide CGM with its Predict App can reduce fear of hypoglycemia and improve related behaviors and confidence in adults with type 1 or insulin-treated type 2 diabetes.
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Ashwagandha with resistance training to boost strength and stress markers
This 12-week study tests whether taking ASHWAGANDHA along with regular resistance training helps healthy, trained men see improvements in strength, stress levels, sleep, and cognitive function compared with a placebo.
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Acupoint Stimulation and Exercise for Pre-frail Older Adults in Taiwan
This study tests whether combining exercise with daytime and sleep-improving acupoint stimulation helps pre-frail adults 50 and older in Taiwan feel less frail and sleep better.
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Sleep and Chronotype linked to Prosocial Choices
This observational study tests whether people’s sleep quality and chronotype relate to how they decide to allocate money in a hypothetical task.
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Digital and Plasma Biomarkers for Delirium in the ICU
This study tests whether digital biomarkers and blood biomarkers can help detect and predict delirium in older adults in the ICU.
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Mindfulness Meditation for Hemodialysis Patients
A small trial tests whether a 4-week mindfulness meditation program in addition to usual care can improve sleep quality and reduce stress and symptoms in adults on hemodialysis.
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Bruxism Therapy with a Splint for Facial Pain
This study tests whether wearing a night-time occlusal splint changes jaw muscle activity in adults with temporomandibular disorders and chronic jaw pain, using a portable EMG device to track activity over 24 hours.
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See if reducing heat and air pollution helps pregnant women sleep better
This study tests whether a mix of tips and devices to lower personal heat and indoor air pollution can improve sleep quality for pregnant women.
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CBD for sleep after late-evening workouts
This trial tests whether taking CBD after a late-evening high-intensity workout helps healthy, recreationally active adults aged 18–40 sleep better.
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Time-restricted eating and 24-hour activity patterns in college-aged women
This trial will test whether limiting eating to a daily 4–12 hour window changes sleep, physical activity, and sedentary behavior in female University of Georgia students aged 18–26.
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L. reuteri LM1063 for improving sleep
This trial will try a daily L. reuteri LM1063 probiotic to see if it helps adults (19–65) with poor sleep get better sleep.
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Social media diet to reduce loneliness, FoMO, and improve sleep in university students
This trial will test whether a 4-week social media diet can reduce loneliness and fear of missing out (FoMO) and improve sleep quality in university students who use social media at least 2 hours per day.
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Relationship Between Gum Disease and Sleep Quality
This project will see if periodontitis and saliva inflammation markers (IL-6, IL-10, pentraxin-3) are linked to poorer sleep quality and greater fatigue in adults.
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Self-acupressure to improve social jet lag in female health sciences students
This randomized trial tests whether daily self-acupressure can improve social jet lag and sleep quality in 18-25 year-old female health sciences students compared with a sham procedure.
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Sleep quality and cognitive function in young adults
We will see if sleep quality, measured by a five-day wearable and a short sleep questionnaire, is linked to attention, thinking skills, and memory in healthy young adults.
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Home-based inspiratory muscle training to lower dementia risk in older adults
This study will test whether an 8-week, daily home inspiratory breathing program can lower blood pressure and improve thinking, mood, and sleep in adults aged 60–80 who have risk factors for dementia.
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Nutritional supplement to improve sleep quality
This trial will test whether a new powdered dietary supplement helps adults ages 35–65 with mild sleep problems sleep better than a placebo.
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Sleep quality improvement with a multimodal pathway after orthopedic trauma
This study tests whether a multimodal sleep pathway ( zolpidem, melatonin, and sleep hygiene education ) can improve sleep and reduce opioid use for patients recovering from orthopedic trauma in the hospital.
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Massage to improve sleep, comfort, and vital signs in preterm infants
This trial will see if giving medically stable preterm infants (35–37 weeks) a 15-minute massage three times a day for three days in the NICU improves sleep, reduces stress, increases comfort, and stabilizes vital signs compared with standard care.
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Smartwatch checks for vitals, anxiety, and sleep before disc surgery
This project will test whether Samsung smartwatches can accurately measure blood pressure, heart rate, oxygen levels, anxiety, and sleep in adults preparing for disc herniation surgery.
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Think Tank nutritional drink to help thinking after stress in middle-aged women.
This trial will test whether taking the 'Think Tank' nutritional drink helps thinking and mood after a physical and psychological stressor in healthy women aged 40–60 who drink caffeine daily.
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Schroth three-dimensional exercises for adolescents with thoracic hyperkyphosis
This program will test whether Schroth three-dimensional exercises can improve trunk muscle endurance, sleep quality, and quality of life in adolescents aged 12–18 with thoracic hyperkyphosis.
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Home ventilation and air cleaner for asthma in low-income DFW homes
This trial will test whether installing whole-home energy recovery ventilators or portable air cleaners in low-income Dallas–Fort Worth homes lowers indoor pollutants and improves asthma symptoms and quality of life over one year.
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Daily step counts and treatment response in early HER2‑negative breast cancer
This project will try to see if daily step counts from a Huawei smartwatch can predict how well people with non-metastatic HER2‑negative breast cancer respond to chemotherapy given before surgery.
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Cystic Fibrosis Wellness Program for Adults with Fatigue
This pilot randomized trial will try a combined cognitive behavioral therapy and physical activity coaching program to see if it helps adults with cystic fibrosis who have significant fatigue sleep better, move more, and sit less.
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Scaling a healthy sleep program for vocational secondary school students
This project will try delivering a healthy sleep program and teacher training to 12–14-year-old vocational students and their teachers to improve sleep quality.
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Using a wireless ANNE One vital-sign device array to reduce bedside vital-sign measurement time
This trial will see if using a wireless Bluetooth ANNE One vital-sign device array reduces the time staff spend obtaining and charting vital signs for adult inpatients on a general medical floor.
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Effects of intermittent fasting on sleep and quality of life
This study is testing if different schedules of intermittent fasting can improve sleep quality and overall well-being in healthy volunteers.
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SIESTA: A sleep hygiene program for urban Latino middle schoolers
This program tests whether a culturally tailored, school-based sleep hygiene intervention (SIESTA) helps urban Latino middle schoolers ages 11–13 sleep longer and improve sleep habits compared with a health education control.
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Ear massage to reduce stress, anxiety, and improve sleep in parents of children with Type 1 diabetes
This study is testing if giving themselves ear massages can help parents of children with Type 1 diabetes feel less stressed and anxious, and sleep better.
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Exploring how sleep quality affects self-care in heart failure patients
This study looks at how the quality of sleep affects self-care habits in people with heart failure over six months.
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Using light to improve well-being and sleep quality for radiographers
This study tests if different lighting conditions can help radiographers feel better and sleep more soundly during the darker months of the year.
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Effects of Cool Roofs on Health and Indoor Environments
This study is testing if special cool roofs that reflect sunlight can help people living in hot urban areas feel better and stay healthier by reducing heat exposure.
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Exploring sleep disorders in ulcerative colitis patients
This study looks at how sleep problems affect people with ulcerative colitis and what that means for their overall health and gut bacteria.
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Improving quality of life for breast cancer patients using real-world data
This study tests if using the REBECCA system to provide support for breast cancer patients after treatment can improve their quality of life compared to standard care.
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Transcranial Direct Current Stimulation for Long COVID with Headaches and Chronic Pain
This study tests whether applying mild brain stimulation (tDCS) can help people with long COVID who have headaches, migraines, and ongoing pain.
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Examining how carpal tunnel syndrome affects sleep quality
This study looks at how carpal tunnel syndrome affects sleep quality in patients compared to healthy people to see if there's a connection between the two.
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Effects of Nicotinamide Riboside on Cognition and Sleep in Older Adults
This study is testing if taking nicotinamide riboside can improve thinking skills and sleep quality in older adults who have trouble with both.
NIH-funded research (7)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Improving Sleep for Nursing Home Residents with Dementia
A real-world program helps nursing homes use a simple staff approach called LOCK to improve sleep for residents with dementia.
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Better sleep for students starting college
This project tries a brief, six-week mindfulness program to help college students sleep better during their move to campus.
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How neighborhood environments affect depression in adolescent girls
This study is exploring how things in your neighborhood, like parks and community centers, can impact the mental health of teenage girls, especially when considering changes during puberty and sleep quality, to find ways to help them feel better and stronger against depression.
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Improving sleep quality in veterans with PTSD using vagal nerve stimulation
This study is looking at how a gentle electrical stimulation technique can help veterans with PTSD sleep better, especially those who may also have had a mild brain injury, by improving their sleep patterns and overall well-being.
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Improving sleep quality for nursing home residents with dementia
This study is testing a new program called LOCK to help nursing home staff create a better sleep environment for residents with Alzheimer's and related dementias, aiming to improve their sleep and overall well-being by reducing noise and light disturbances.
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Improving sleep quality for college students
This study is looking at how a six-week mindfulness program can help college students sleep better and feel healthier, making it easier for them to manage the sleep problems many of them face.
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Investigating the link between sleep quality and Alzheimer's disease in older Mexican Americans and Non-Hispanic Whites
This study is looking at how the quality of sleep might influence the chances of older Mexican Americans and Non-Hispanic Whites developing Alzheimer's and similar conditions, hoping to find ways to improve sleep and help protect brain health.
Related topics
Quick answers
How many Sleep Quality clinical trials are recruiting right now?
40, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 20 countries. The most sites are in Turkey (Türkiye) (13 trials), United States (10 trials), Belgium (3 trials), Cyprus (2 trials), Italy (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.