Comparing ultrasound-guided injections to surgery for carpal tunnel syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare the effectiveness of ultrasound-guided perineural injections of the median nerve with minimal incision surgery for median nerve decompression in patients diagnosed with mild, moderate, or severe carpal tunnel syndrome. Carpal tunnel syndrome is a common condition that causes sensory and motor symptoms due to compression of the median nerve. Participants will be evaluated based on their symptoms and electrophysiological testing to determine the severity of their condition. The study will assess which treatment option provides better relief from symptoms and improves function.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* The presence of symptoms such as nocturnal, posture-related, or movement-related paresthesias, along with possible pain, in the area supplied by the median nerve in the hand, lasting for more than 3 months.
* Confirmation of mild, moderate or severe CTS through electrophysiological testing.
* Numbness and loss of sensation in the hand's regions innervated by the median nerve, as well as weakness in the thenar muscles innervated by the median nerve.
* Positive results on either the Phalen test and/or Tinel sign.

Exclusion Criteria:

* Individuals who may exhibit symptoms mimicking carpal tunnel syndrome, such as cervical radiculopathy, polyneuropathy, brachial plexopathy, or thoracic outlet syndrome.
* Patients who have received a previous injection into the carpal tunnel within the past 6 months.
* Thenar muscle atrophy.
* A history of prior carpal tunnel surgery.
* Regular usage of systemic nonsteroidal anti-inflammatory drugs and corticosteroids.
* Pregnancy
* Patients diagnosed with rheumatoid arthritis, systemic lupus erythematosus, gout, systemic sclerosis, dermatomyositis, or polymyositis.
* Malignancy.
* Active infections

Where it's running

• Afyonkarahisar Health Sciences University
  Afyonkarahisar, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Nuran EYVAZ, MD — Afyonkarahisar Health Sciences University
• Study coordinator: Ali İzzet AKÇİN, MD
• Email: dr.akcin93@gmail.com
• Phone: +905469347374

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.