Comparing ultrasound-guided corticosteroid injections and paraffin therapy for carpal tunnel syndrome

Comparison of the Efficacy of Ultrasound-Guided Corticosteroid Injection and Paraffin Therapy in Carpal Tunnel Syndrome

Observational Beylikduzu State Hospital · NCT06658886

This study is testing whether ultrasound-guided corticosteroid injections or paraffin therapy works better to relieve pain and improve function in people with mild to moderate carpal tunnel syndrome.

Quick facts

Study typeObservational
Enrollment46 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorBeylikduzu State Hospital Academic / other
Locations1 site (Istanbul, Beylikdüzü)
Trial IDNCT06658886 on ClinicalTrials.gov

What this trial studies

This study aims to compare the effectiveness of two treatments for carpal tunnel syndrome: ultrasound-guided corticosteroid injections and paraffin therapy. A total of 46 patients aged 18-65 with mild to moderate carpal tunnel syndrome will be evaluated based on pain levels and functional impairment using standardized questionnaires and electrophysiological assessments. Follow-ups will occur at 1, 3, and 12 weeks post-treatment to measure outcomes. The goal is to determine which treatment offers better relief and functionality for patients suffering from this common condition.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18-65 diagnosed with mild to moderate carpal tunnel syndrome who have had symptoms for at least 3 months.

Not a fit: Patients with other neuropathic conditions or those who have previously undergone surgery or injections for carpal tunnel syndrome may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide patients with effective low-side-effect treatment options for managing carpal tunnel syndrome.

How similar studies have performed: While there have been studies on corticosteroid injections for carpal tunnel syndrome, the comparison with paraffin therapy is less common, making this approach somewhat novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged 18-65.
* Diagnosed with mild to moderate carpal tunnel syndrome based on electrophysiological studies.
* Received either ultrasound-guided corticosteroid injection or paraffin therapy.
* Symptoms persisting for at least 3 months.

Exclusion Criteria:

* Diagnosis of other conditions causing neuropathic symptoms (e.g., polyneuropathy, brachial plexopathy, thoracic outlet syndrome).
* History of previous injection or surgery for carpal tunnel syndrome.

Where this trial is running

Istanbul, Beylikdüzü

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Carpal Tunnel Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.