Understanding how aging cells contribute to Carpal Tunnel Syndrome
The Role of Cellular Senescence in Carpal Tunnel Syndrome
['FUNDING_R01'] · MAYO CLINIC ROCHESTER · NIH-10996173
This study is looking at how aging cells might play a part in causing Carpal Tunnel Syndrome, which affects many people, and it aims to find ways to treat this condition by focusing on those aging cells to help improve symptoms for patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAYO CLINIC ROCHESTER (nih funded) |
| Locations | 1 site (ROCHESTER, UNITED STATES) |
| Trial ID | NIH-10996173 on ClinicalTrials.gov |
What this research studies
This research investigates the role of cellular senescence, or the aging of cells, in the development of Carpal Tunnel Syndrome (CTS), a common condition affecting millions of Americans. The study aims to understand how the accumulation of senescent cells in the connective tissue around the median nerve contributes to the fibrosis and symptoms associated with CTS. By examining tissue samples from CTS patients, researchers will explore the mechanisms behind this condition and test potential treatments that target these aging cells to improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Carpal Tunnel Syndrome, particularly those experiencing symptoms related to aging.
Not a fit: Patients who do not have Carpal Tunnel Syndrome or those with acute injuries unrelated to aging may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that alleviate the symptoms of Carpal Tunnel Syndrome and improve the quality of life for affected patients.
How similar studies have performed: Previous research has shown promise in targeting cellular senescence for various age-related conditions, suggesting that this approach may be effective for Carpal Tunnel Syndrome as well.
Where this research is happening
ROCHESTER, UNITED STATES
- MAYO CLINIC ROCHESTER — ROCHESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GINGERY, ANNE — MAYO CLINIC ROCHESTER
- Study coordinator: GINGERY, ANNE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: age associated chronic disease, age associated chronic disorder, age associated disease, age associated disorder