Condition

Cardiometabolic Health clinical trials and research

• 11Clinical trials
• 116NIH research projects
• 1New in 30 days
• 4Countries

Newest Cardiometabolic Health clinical trials

All recruiting trials (11)

• Postpartum exercise to improve heart and metabolic health in women at high risk for preeclampsia

  This pilot study tests whether a 12‑week postpartum exercise program can improve heart health and metabolic markers in women who were at high risk for preeclampsia.

  Recruiting Chinese University of Hong Kong · Hong Kong, Hong Kong · NCT07921173

• See if short bursts of activity every day improve fitness and health in inactive young adults

  This study tests whether short, frequent bouts of exercise throughout the day can boost activity levels, fitness, and health in adults who aren’t currently active.

  Recruiting University of Wisconsin, River Falls · River Falls, Wisconsin · NCT07718113

• Does daily lean beef support brain health in older adults

  In healthy adults aged 65 and up, this study tests whether eating lean beef every day for two weeks can influence brain health markers compared with a non-beef, protein-matched option.

  Recruiting South Dakota State University · Brookings, South Dakota · NCT07623785

• Potato-rich diet for cardiometabolic health in adults with type 2 diabetes risk

  This study tests whether a potato-rich healthy eating pattern can improve cardiometabolic health in adults aged 50–70 who are at risk for type 2 diabetes but not yet diagnosed.

  Recruiting Virginia Polytechnic Institute and State University · Blacksburg, Virginia · NCT07229482

• Animal versus plant protein smoothies and their effects on metabolism and immune signaling

  This trial will test whether drinking animal-based, plant-based, or plant-based plus leucine protein smoothies changes blood amino acids and metabolic and immune responses in healthy adults.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT07121010

• Neighborhood and Health: Living in an Agrihood Community

  This project will test whether living in a new agrihood helps adults improve healthy eating, physical activity, cardiometabolic health, and social connections compared with a nearby similar neighborhood.

  Recruiting at 2 sites Texas A&M University · Katy, Texas and 1 other locations · NCT06950775

• Impact of a school-based fruit and vegetable program on child and parent health in low-income areas

  This study is testing whether a program that gives fresh fruits and vegetables to kids and their families can improve their health and eating habits in low-income areas.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06570707

• Effects of Sleep Regularity on Heart and Metabolic Health

  This study is testing if sticking to a regular sleep schedule can improve heart and metabolic health in healthy adults aged 18 to 40.

  Recruiting Oregon Health and Science University · Portland, Oregon · NCT06535178

• Personalized plant-based diet to improve heart and metabolic health

  This study is testing if a personalized plant-based diet high in certain compounds can improve heart and metabolic health in people at risk for these issues.

  Recruiting at 2 sites University of Parma · Parma, PR and 1 other locations · NCT06347094

• Assessing heart disease and diabetes risk in women during and after pregnancy

  This study is trying to see how pregnancy complications like pre-eclampsia affect women's chances of developing heart disease and diabetes later on, by following women who are trying to get pregnant and comparing them to those who aren't.

  Recruiting at 3 sites Cambridge University Hospitals NHS Foundation Trust · Cambridge and 6 other locations · NCT05856318

• Improving heart and metabolic health with HEPA air purifiers

  This study is testing if using HEPA air purifiers can improve heart and metabolic health in non-diabetic adults aged 65 to 84 by reducing indoor air pollution.

  Recruiting University of Southern California · Los Angeles, California · NCT05718245

NIH-funded research (newest 40 of 116)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Preterm infant body composition and early-life health after NICU stay

  This grant studies how body composition in very preterm babies relates to later brain development and risk of obesity or diabetes, with findings meant to improve care from NICU through early childhood.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11600939

• Psychosocial and cultural factors linked to heart and metabolic health in older Chinese Americans

  This project studies how daily stress and social factors affect heart and metabolic health in older Chinese Americans, using real-time reporting and biosamples.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11543751

• Early life factors shaping heart health in HIV-exposed versus unexposed kids in South Africa

  A study following children from birth through adolescence to understand how HIV exposure and early infections influence heart-related health risks.

  NIH research Hartford Hospital · Hartford, United States · NIH-11474039

• Early-life factors shaping heart health in HIV-exposed and unexposed children in South Africa

  This project follows children from birth through adolescence to understand how being exposed to HIV before birth affects their metabolic and heart health over time.

  NIH research Hartford Hospital · Hartford, United States · NIH-11474038

• Promoting steady activity for adults with obesity through PATH-powered exercise videos and remote coaching

  A weight-neutral online program called PATH uses YouTube workout videos and remote coaching to help adults with obesity stay active and improve heart health over a year.

  NIH research Emory University · Atlanta, United States · NIH-11450535

• Morning light to improve heart and blood sugar health in adults with Type 1 Diabetes

  A small trial tests whether morning bright light can improve blood sugar control and blood pressure in adults with Type 1 Diabetes.

  NIH research Northwestern University · Chicago, United States · NIH-11445915

• Ultra-processed foods, diet quality, and heart health: a trans-Atlantic study

  This NIH grant funds a study to understand how ultra-processed foods affect weight and heart-related health, and whether improving overall diet quality can offset any negative effects.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11417458

• Apolipoprotein Proteoforms and Heart Health

  This grant aims to understand how different chemical changes to apolipoproteins relate to cholesterol, obesity, insulin resistance, and risk of heart disease in people.

  NIH research Northwestern University · Chicago, United States · NIH-11417166

• Early life factors shaping heart health in HIV-exposed and unexposed children in South Africa

  This grant follows children born in South Africa to see how early life infections and HIV exposure affect inflammation and markers of heart health from infancy through adolescence.

  NIH research Hartford Hospital · Hartford, United States · NIH-11415822

• Improving Cardiometabolic Health with Meditative Movement for Mobility-Impaired Women

  Aimed at mid-life women with mobility impairments, this project tests whether seated Tai Chi and Qigong can reduce belly fat and stress to lower cardiometabolic risk.

  NIH research Arizona State University-Tempe Campus · Scottsdale, United States · NIH-11411335

• MAGIC-PHIV: Microbiome, Gut Inflammation, and Metabolic Health in Youth with Perinatally Acquired HIV

  A short, friendly project will study gut health and microbial changes in young people with perinatally acquired HIV to understand links to heart and metabolism as they grow.

  NIH research Lurie Children's Hospital of Chicago · Chicago, United States · NIH-11400032

• Multilevel factors shaping sleep and circadian disruption in African-Americans and its impact on heart and metabolism

  This research looks at how everyday environments like home lighting, noise, and air pollution affect sleep and circadian rhythms in African-American adults and how these patterns relate to heart and metabolic health.

  NIH research Emory University · Atlanta, United States · NIH-11397747

• Early-life influences on heart and metabolic health in South African children exposed to HIV

  This project follows children born in South Africa—some exposed to HIV but uninfected and some not exposed—to see how early infections and immune changes shape inflammation and metabolism up to early adolescence.

  NIH research Hartford Hospital · Hartford, United States · NIH-11394077

• How early-life infections and HIV exposure shape heart and metabolic health in South African children

  Tracking how early infections and HIV exposure affect metabolism and early heart health in South African children from birth through early adolescence.

  NIH research Hartford Hospital · Hartford, United States · NIH-11394076

• Lipid and DNA Insights into Heart and Metabolic Health in Samoan Adults

  This research will study how fats in the blood and genetic differences relate to diabetes and heart health in Samoan adults.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11393301

• Sleep patterns linked to heart health in younger women

  This project looks at how sleep quality and variability relate to heart health risks in women aged roughly 35–54.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11392698

• Trauma, stress, and heart health in an American Indian community

  This NIH grant aims to understand how trauma affects heart and mental health among American Indian adults in Montana.

  NIH research Montana State University - Bozeman · Bozeman, United States · NIH-11392272

• Joint effects of early lead exposure and psychosocial stress on teen health

  This project looks at how early life lead exposure and psychosocial stress together affect stress responses and future heart and metabolic health in teens.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11391205

• Sleep health in rural communities and its links to heart and blood vessel disease

  A study in rural Southern communities will track how sleep patterns relate to cardiometabolic health to better understand why this population bears a higher burden of disease.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11391096

• In-home HEPA filtration to slow biological aging and improve heart and lung health in older adults with eosinophilic COPD

  A 12-month in-home HEPA filter trial in older adults with eosinophilic COPD examines whether cleaner indoor air can slow aging markers and improve heart and lung health.

  NIH research Stanford University · Stanford, United States · NIH-11390736

• Endowment to Build Cardiometabolic Health Research Capacity at MMC

  A grant to Meharry Medical College to expand cardiometabolic health research and training, with goals to boost capacity in Nashville and Davidson County.

  NIH research Meharry Medical College · Nashville, United States · NIH-11387690

• Psychosocial and cultural factors shaping heart and diabetes risk in older Chinese Americans

  This study looks at how daily stress and culture affect heart and diabetes health in older Chinese Americans who were born outside the U.S.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11383449

• How food security affects heart and metabolic health in Puerto Rico

  This project follows adults in Puerto Rico to show how unreliable access to healthy food may raise the chances of type 2 diabetes and heart disease.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11382777

• Improving sleep to reduce heart and metabolic risks in Latinx adults

  This program offers a culturally adapted sleep-health intervention to help Latinx adults improve blood pressure and blood sugar by improving sleep duration, regularity, and quality.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11380509

• Sex differences in cardiometabolic health and disease

  A nationwide effort will study why men and women differ in cardiometabolic disease, aiming to improve diagnosis and treatment for both sexes.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11378200

• Understanding how sleep and daily rhythms affect heart and metabolic health

  A study from Columbia aims to uncover how lack of sleep and misaligned daily schedules influence obesity, blood pressure, and heart disease risk, by looking at daily patterns of eating, activity, and sleep.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11370292

• Childhood obesity and cardiometabolic health in Latino youth from low-income families

  This project follows Mexican American kids from birth through mid-adolescence to understand how weight and heart health develop over time.

  NIH research Arizona State University-Tempe Campus · Scottsdale, United States · NIH-11369846

• How early lead exposure and childhood stress affect heart and metabolic health

  This project looks at whether lead exposure and stressful or supportive experiences in early life alter stress biology and raise the risk of heart and metabolic problems in adolescents and young adults.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11369536

• Comprehensive periodontal care to help prediabetes and gum health

  A new Mayo Clinic study will test whether comprehensive gum treatment can slow the worsening of blood sugar and gum disease in adults with prediabetes.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11366654

• Genetic clues to heart health: how ANP and microRNA affect metabolism in adults

  A study in healthy adults looks at how a common ANP gene variant and a microRNA interact with glucose and exercise to influence heart-related metabolism and energy use.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11352520

• Neprilysin Inhibition and Cardiometabolic Health in Black Adults

  This study tests whether the diabetes- and heart-health benefits of an approved drug combination can improve insulin sensitivity and energy use in Black adults with higher risk for cardiometabolic disease.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11332691

• How blood sugar, blood pressure, and body fat over a lifetime affect spine strength

  This project will look at whether long-term heart and metabolic health in adults is linked to weaker bones in the spine.

  NIH research Tulane University of Louisiana · New Orleans, United States · NIH-11319047

• Phthalate exposure during pregnancy and after birth and mothers' heart and metabolic health

  Researchers are looking at whether common plastics chemicals called phthalates during pregnancy and the postpartum period are linked to changes in mothers' weight, blood sugar, inflammation, and heart health.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11312583

• How early life affects heart and metabolic health in children exposed to HIV at birth

  Tracking how being born to an HIV-positive mother and early childhood infections change metabolism and heart-risk markers from birth through early adolescence in South African children.

  NIH research Hartford Hospital · Hartford, United States · NIH-11303481

• Recipe4Health program for weight and heart health

  This project compares Medi‑Cal patients who get Recipe4Health’s produce prescriptions and health coaching with similar patients who don’t, to see if it helps weight and heart-related health.

  NIH research Stanford University · Stanford, United States · NIH-11290301

• Culturally adapted Mediterranean-style diet for heart and metabolic health in Puerto Rico

  This program offers a Puerto Rico–adapted Mediterranean-style eating plan to adults 30–65 with at least one heart or diabetes risk factor to improve blood pressure, cholesterol, and overall metabolic health over two years.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11289357

• Lifestyle program to improve heart and metabolic health in women ages 18–25

  Helps women ages 18–25 improve sleep, diet, activity, and stress to lower inflammation and reduce future risk of heart and metabolic disease.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11286808

• How exercise may improve heart and metabolic health for night shift workers

  A small proof-of-concept study will test if a guided aerobic exercise routine can help prevent heart and metabolic problems in adults who regularly work night shifts.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11282877

• How estrogen and heart/metabolic health affect memory in aging women

  This project is seeing if estrogen treatment protects thinking and memory in older women and whether conditions like diabetes or high blood pressure change that effect.

  NIH research Tulane University of Louisiana · New Orleans, United States · NIH-11269206

• WATCH: Community exercise, education, and support program to improve heart and metabolic health for wheelchair users

  This program offers supervised, accessible exercise plus education and support to help adults who use wheelchairs improve their heart and metabolic health.

  NIH research Washington University · Saint Louis, United States · NIH-11262805

Related topics

Quick answers

How many Cardiometabolic Health clinical trials are recruiting right now?

11, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (8 trials), United Kingdom (1 trial), Italy (1 trial), Hong Kong (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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