Postpartum exercise to improve heart and metabolic health in women at high risk for preeclampsia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The study enrolls 40 women 6 to 8 weeks after delivery who had a hypertensive disorder of pregnancy and are at high risk for preeclampsia. Participants are randomized to a 12‑week program of aerobic, resistance, and pelvic floor exercises three times per week or standard postnatal care. Outcomes include cardiovascular function, blood pressure, metabolic blood markers, fitness, body composition, mood, sleep, and health-related quality of life, measured before and after the program. The trial aims to determine if structured postpartum exercise can benefit cardiometabolic health in this high‑risk population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged 18 to 45 years.
* Identified as being at high risk for preeclampsia during the most recent pregnancy and developed a hypertensive disorder of pregnancy (HDP).
* Had a singleton pregnancy.
* 6 to 8 weeks postpartum at enrollment.
* Physically able to participate in the exercise training program.
* Willing to participate in the study and provide informed consent.

Exclusion Criteria:

* Had a multiple pregnancy.
* Severe medical complications after delivery or other health conditions that contraindicate physical exercise (e.g., severe cardiovascular disease or musculoskeletal disorders).
* Chronic hypertension or diabetes before pregnancy.
* Current use of medication that could potentially affect cardiac function (e.g., medication for heart failure).
* Received antibiotic treatment within the past month.
* Severe mental health disorders that affect the ability to exercise.
* Unable or unwilling to adhere to and attend the 12-week exercise program.

Where it's running

• Department of Obstetrics & Gynaecology, Prince of Wales Hospital
  Hong Kong, Hong Kong, Hong Kong Recruiting

Study contacts

• Study coordinator: Yao Wang, PhD
• Email: yaowang1@cuhk.edu.hk
• Phone: +85235051289

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.