Joint effects of early lead exposure and psychosocial stress on teen health
Official title: Joint effects of early life Pb and psychosocial exposures on stress and cardiometabolic health
Funded at University of Michigan at Ann Arbor · NIH-11391205 · Data updated 2026-11-12
This project looks at how early life lead exposure and psychosocial stress together affect stress responses and future heart and metabolic health in teens.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | March 20, 2025 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $248,999 |
| NIH project number | 5R00ES036294-03 |
| Project ID | NIH-11391205 on NIH RePORTER |
Who could benefit from this research
✓Could help
Teens and adolescents who had early life lead or metal exposures and are part of the study’s follow-up cohorts.
✕Less likely to help
If a teen did not have significant early exposures or is not in the follow-up group, direct benefits may be limited.
What this research studies
If your child was exposed to lead early in life and also faces stress from their environment, this study will track health markers over time to see how these exposures interact. Researchers will analyze data on lead and other metals, stress factors, and biological responses to understand who might be at higher risk for metabolic and cardiovascular issues as they grow. The work uses existing cohorts and follow-up visits to connect early exposures with later health outcomes, aiming to identify protective factors as well. Results could point to strategies for reducing risk and guiding healthier development.
Why it matters
Potential benefit: Better understanding of how combined early exposures affect teen health could lead to targeted prevention and intervention strategies.
How similar studies have gone: There is evidence that single exposures affect health, but this study explores the combined effects in humans, which is novel.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Halabicky, Olivia Maryfrances — University of Michigan at Ann Arbor
- Study coordinator: Halabicky, Olivia Maryfrances
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.