Sponsor or institution
Clinical trials and research at Stellenbosch University
As of November 12, 2026, Find a Trial lists 35 NIH-funded research projects at this institution, with $9.4 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 35NIH research projects
NIH-funded research (35)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Harnessing male peer networks to boost HIV testing and PrEP use
A large clinical trial in South Africa tests whether giving HIV self-test kits through male peer networks, with phone support, increases PrEP uptake among men.
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Harnessing men's peer networks to boost HIV self-testing and PrEP use
A large project in South Africa tests whether giving HIV self-test kits through men’s social networks, with phone support, can lead to more men starting PrEP and using HIV testing.
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Identifying biomarkers that predict TB disease risk in children with HIV
Researchers will study stored samples from young children, including those with HIV, to find biological markers that signal who might develop TB or respond to treatment.
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Identifying biomarkers to predict tuberculosis risk in kids and HIV patients
Researchers will study stored samples from young children and people with HIV to find biomarkers that signal who might progress to active TB and how they respond to treatment.
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Targeting rising HIV risk groups in rural South Africa during COVID-19
This project will find which people and places in rural KwaZulu-Natal are now most at risk of getting HIV so prevention can be aimed where it will help the most.
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Reducing new HIV infections in rural South Africa after COVID-19
This project finds who in rural KwaZulu-Natal is now most at risk for HIV so prevention efforts can be focused to stop new infections.
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Understanding brain injury in kids with tuberculous meningitis (iThemba)
A study in children with TB meningitis in South Africa will look at how inflammation and blood-clotting factors relate to brain injury and infarcts.
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Harnessing male peer networks to boost HIV testing and PrEP use
A large community study in South Africa tests if giving HIV self-test kits through male peers, with support by phone, can increase HIV testing and PrEP uptake among men.
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Finding biological signs that predict which TB-exposed children will get sick
This project looks for blood and other biological signs in children exposed to tuberculosis that show who is likely to develop TB disease.
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Using men's social networks to increase HIV self-testing and PrEP use
This project offers HIV self-test kits through men's social networks with phone support to help men in eastern Zimbabwe get tested and start PrEP.
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Using men's social networks to boost HIV self-testing and PrEP uptake
This project helps men in eastern Zimbabwe get HIV self-test kits and phone-based support from male peers to increase starting HIV prevention medicine (PrEP).
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Understanding brain injury in children with tuberculous meningitis
This project studies how TB meningitis causes brain injury in children and how this disease progresses over time.
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Health and development of children born exposed to HIV but uninfected
This project follows children born in the Western Cape to compare survival, hospital visits, growth, and development between those exposed to HIV before birth who are uninfected and children not exposed to HIV.
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Brain blood flow and clotting problems in children with tuberculous meningitis
This project looks at why some children with tuberculous meningitis get brain infarcts by using scans and tests of blood and spinal fluid.
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How HIV risk is changing after COVID‑19 and focusing prevention in rural South Africa
This project uses long-term community health data to spot who in rural KwaZulu‑Natal is now most likely to get HIV so prevention can be aimed where it's needed most.
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Stellenbosch University clinical trials unit for HIV and TB
This Cape Town program runs clinical research to test better HIV and TB prevention and treatment options for children, adolescents, and adults.
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Why children with tuberculous meningitis develop brain ischemia
Researchers will collect brain scans, blood, and spinal fluid from children with tuberculous meningitis to learn what triggers strokes and long-term disability.
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Understanding Gut Health and Treatment for Drug-Resistant Tuberculosis
This project looks at how gut bacteria change during treatment for drug-resistant tuberculosis to help us understand patient health.
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Health of children exposed to HIV before birth
This project compares long-term survival, hospital visits, growth, and development in children born to mothers with HIV but who are themselves uninfected versus children not exposed to HIV in South Africa.
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Using male peer networks to boost HIV self-testing and PrEP use
Men in eastern Zimbabwe will be offered HIV self-tests through their social networks plus phone support to help them know their status and start PrEP if appropriate.
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Training to understand HIV's effects on mothers and infants
This study is all about helping healthcare workers learn more about how HIV in pregnant women can affect their babies, with the goal of finding better ways to support mothers and infants facing these challenges.
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Better tests to find and monitor tuberculosis
This project aims to bring easier, faster TB tests to people in low-resource areas so active, new, and returning TB can be found and treated sooner.
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Understanding and reducing HIV risk in older populations during the COVID-19 pandemic.
This study looks at how the COVID-19 pandemic has changed the way HIV spreads, especially among older people in South Africa, and aims to find new ways to help prevent infections in rural communities.
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Assessing heart health in HIV-infected individuals before and after starting treatment
This study is looking at heart health in people with HIV in South Africa to find any early signs of heart problems before they start treatment, and it will also see how starting treatment affects their heart over time, all while helping local doctors learn better ways to spot and treat these issues.
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Investigating how DNA changes affect tuberculosis bacteria's ability to survive antibiotics
This study is looking at how a chemical change in the DNA of tuberculosis bacteria helps them survive antibiotics, with the hope that the findings will lead to better treatments for patients with tuberculosis.
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Investigating health outcomes in children exposed to HIV but uninfected
The CHERISH project is looking at the long-term health of children in South Africa who were exposed to HIV before birth but are not infected, to see how they grow and develop compared to kids who weren't exposed, with the goal of finding ways to better support their health.
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Understanding how adherence to HIV treatment affects stroke risk in patients
This study is looking at how sticking to HIV treatment might affect the risk of having a stroke in people living with HIV who are doing well with their viral load, especially in South Africa, where both HIV and stroke are big health concerns.
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Exploring ethical data science practices in Southern Africa
This study is looking at how data science affects people in Southern Africa and wants to hear from the community about their experiences, so we can create helpful guidelines for using data responsibly and ethically.
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Investigating the long-term effects of tuberculosis and respiratory viruses on lung health in young children in South Africa
This study is looking at how lung infections like tuberculosis and respiratory viruses impact the health of young children in South Africa, with the goal of finding ways to improve their care and lung health in the future.
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A test to check if patients are taking their HIV medication as prescribed
This study is working on a simple and affordable test that uses urine samples to quickly check if people with HIV are taking their medication as prescribed, so doctors can give them the support they need to stay healthy.
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Investigating how antibiotics affect the microbiome in drug-resistant tuberculosis patients
This study is looking at how the bacteria in your body might change when you start taking antibiotics for drug-resistant tuberculosis, and it’s for adults and teens who are beginning this treatment.
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Using engineered nanoparticles to fight tuberculosis
This study is looking at how tiny particles can help boost the immune system's ability to fight tuberculosis, especially for people whose immune systems are weaker, by making it easier for immune cells to target and kill the bacteria.
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Understanding why HIV-infected women in South Africa have adverse birth outcomes
This study is looking at how certain factors might affect pregnancy outcomes for women with HIV in South Africa, focusing on the health of both mothers and their babies, to help find ways to prevent complications during pregnancy.
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Understanding the impact of childhood tuberculous meningitis on health outcomes.
This study is looking at how childhood tuberculous meningitis affects kids' health, especially in countries with fewer resources, to help create better care and support for those who are sick.
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Investigating how HIV affects heart and metabolic health in older adults in South Africa and Kenya
This study is looking at how living with HIV might affect heart and metabolic health in older adults in South Africa and Kenya, especially by exploring how problems with cell energy might play a role, so if you're part of this community, your insights could help improve understanding and care for these health issues.
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