Investigating health outcomes in children exposed to HIV but uninfected

CHERISH (Children HIV Exposed Uninfected Research to Inform Survival and Health)

NIH-funded research Stellenbosch University · NIH-10909394

The CHERISH project is looking at the long-term health of children in South Africa who were exposed to HIV before birth but are not infected, to see how they grow and develop compared to kids who weren't exposed, with the goal of finding ways to better support their health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionStellenbosch University NIH-funded
Lab location1 site (Stellenbosch, SOUTH AFRICA)
Project IDNIH-10909394 on NIH RePORTER

What this research studies

The CHERISH project focuses on children in South Africa who are exposed to HIV in utero but are uninfected themselves. It aims to evaluate their long-term health outcomes, including survival rates, hospitalization, growth, and neurodevelopment compared to children who were not exposed to HIV. By utilizing advanced observational epidemiologic methods and biostatistical techniques, the research will analyze health data collected from a large cohort of births in the Western Cape Province. This study seeks to provide insights that could improve healthcare strategies for these children.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years who were exposed to HIV in utero but are uninfected.

Not a fit: Patients who are HIV positive or have other significant health conditions unrelated to HIV exposure may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health monitoring and interventions for children exposed to HIV, enhancing their overall health outcomes.

How similar studies have performed: Previous research has shown success in similar observational studies focusing on health outcomes in HIV-exposed populations, indicating that this approach is promising.

Where this research is happening

Stellenbosch, SOUTH AFRICA

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.