Investigating how HIV affects heart and metabolic health in older adults in South Africa and Kenya
Official title: Altered mitochondrial function and HIV-associatedcardiometabolic disease in populations from South Africa and Kenya (MITO-SAKen)
Funded at Stellenbosch University · NIH-10704100 · Data updated 2026-11-12
This study is looking at how living with HIV might affect heart and metabolic health in older adults in South Africa and Kenya, especially by exploring how problems with cell energy might play a role, so if you're part of this community, your insights could help improve understanding and care for these health issues.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stellenbosch University NIH-funded |
| Lab location | 1 site (Stellenbosch, SOUTH AFRICA) |
| Project start | September 12, 2022 |
| Project end | June 30, 2025 |
| Funding year | 2023 |
| Award (this year) | $154,156 |
| NIH project number | 5R21TW012358-02 |
| Project ID | NIH-10704100 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults living with HIV who are experiencing or at risk for cardiometabolic diseases.
✕Less likely to help
Patients who do not have HIV or those who are not in the older adult age group may not benefit from this research.
What this research studies
This research focuses on understanding the relationship between HIV and cardiometabolic diseases, particularly in older adults living in South Africa and Kenya. It aims to explore how mitochondrial dysfunction may contribute to these health issues in people living with HIV. By examining the unique risk factors present in these populations, the study seeks to fill a significant knowledge gap regarding the intersection of HIV and cardiometabolic diseases. Participants may undergo assessments related to their heart health and metabolic function to better understand these conditions.
Why it matters
Potential benefit: If successful, this research could lead to improved management and treatment strategies for older adults living with HIV and cardiometabolic diseases.
How similar studies have gone: Previous studies have indicated a link between mitochondrial dysfunction and cardiometabolic diseases in HIV patients, suggesting that this research builds on established findings.
Where this research is happening
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Stellenbosch University
Stellenbosch, South Africa Active
Researchers
- Principal investigator: Strijdom, Hans — Stellenbosch University
- Study coordinator: Strijdom, Hans
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.