NIH-funded research NIH-funded research

Investigating the long-term effects of tuberculosis and respiratory viruses on lung health in young children in South Africa

Official title: The long-term consequences of pulmonary tuberculosis and respiratory viruses on lung health in young South African children

Funded at Stellenbosch University · NIH-10886715 · Data updated 2026-11-12

This study is looking at how lung infections like tuberculosis and respiratory viruses impact the health of young children in South Africa, with the goal of finding ways to improve their care and lung health in the future.

More Tuberculosis research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionStellenbosch University
NIH-funded
Lab location1 site (Stellenbosch, SOUTH AFRICA)
Project startAugust 1, 2020
Project endJuly 31, 2025
Funding year2024
Award (this year)$112,523
NIH project number5K43TW011028-05
Project IDNIH-10886715 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are young children, particularly those under the age of 11, who have a history of pulmonary tuberculosis or respiratory infections.

Less likely to help

Patients who are older than 21 years or those without a history of tuberculosis or significant respiratory infections may not benefit from this research.

What this research studies

This research focuses on understanding how pulmonary tuberculosis and respiratory viruses affect lung health in young children, particularly in South Africa where these conditions are prevalent. The project aims to gather and analyze long-term health data from children who have experienced these respiratory infections. By employing advanced statistical methods, the research seeks to identify patterns and outcomes that can inform better healthcare practices and policies for vulnerable populations. The ultimate goal is to translate findings into clinical guidelines that improve lung health in children living in low- and middle-income countries.

Why it matters

Potential benefit: If successful, this research could lead to improved lung health outcomes and better healthcare strategies for children affected by tuberculosis and respiratory viruses.

How similar studies have gone: Previous research has shown promising results in understanding the long-term effects of respiratory infections in children, indicating that this approach could yield valuable insights.

Where this research is happening

  • Stellenbosch University
    Stellenbosch, South Africa
    Active

Researchers

  • Principal investigator: Van Der Zalm, Marieke Margreet — Stellenbosch University
  • Study coordinator: Van Der Zalm, Marieke Margreet

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.