Training to understand HIV's effects on mothers and infants
Official title: Next Generation Training in HIV Research: Immunity in the First 1000 days in mother-infant dyads (TIGRIS)
Funded at Stellenbosch University · NIH-11062434 · Data updated 2026-11-12
This study is all about helping healthcare workers learn more about how HIV in pregnant women can affect their babies, with the goal of finding better ways to support mothers and infants facing these challenges.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stellenbosch University NIH-funded |
| Lab location | 1 site (Stellenbosch, SOUTH AFRICA) |
| Project start | April 1, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $302,400 |
| NIH project number | 5D43TW012758-02 |
| Project ID | NIH-11062434 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include pregnant women living with HIV and their infants, particularly in African regions.
✕Less likely to help
Patients who are not pregnant or do not have HIV may not receive direct benefits from this research.
What this research studies
This research focuses on training healthcare professionals to investigate how HIV infection in pregnant women can lead to negative birth outcomes and immune issues in infants. It involves a collaborative effort between Stellenbosch University in South Africa and several prestigious institutions in the US, Canada, and the UK. The program aims to enhance laboratory skills and data analysis capabilities among researchers, ultimately generating new insights into HIV's impact on mother-infant pairs. By fostering international collaboration, the project seeks to improve understanding and treatment of HIV-related complications in early life.
Why it matters
Potential benefit: If successful, this research could lead to improved health outcomes for infants born to HIV-positive mothers.
How similar studies have gone: Previous research has shown success in similar training programs that enhance understanding of HIV's effects on maternal and child health.
Where this research is happening
-
Stellenbosch University
Stellenbosch, South Africa Active
Researchers
- Principal investigator: Gray, Clive Maurice — Stellenbosch University
- Study coordinator: Gray, Clive Maurice
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.